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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 13 of 13. This is the beginning of the thread.
Posted by LastDyingWish on May 10, 2004, at 0:24:21
What is your opinion of selegiline ? I will be taking it for prosexual purposes. 97-99 I used ecstacy and speed heavily, also heavy drinking. I have been clean since then but suffer from mild anxiety and a large dent in my sex drive. Iam looking for a drug that may potentially have the ability to help my brain regain normal function. From my research, selegiline sounds perfect. My only concerns are from my doctor. He believes thier are riks that it may cause movement disorders. Any adivice will be appreciated. thanks
Posted by chemist on May 10, 2004, at 13:25:48
In reply to question to chemist, posted by LastDyingWish on May 10, 2004, at 0:24:21
> What is your opinion of selegiline ? I will be taking it for prosexual purposes. 97-99 I used ecstacy and speed heavily, also heavy drinking. I have been clean since then but suffer from mild anxiety and a large dent in my sex drive. Iam looking for a drug that may potentially have the ability to help my brain regain normal function. From my research, selegiline sounds perfect. My only concerns are from my doctor. He believes thier are riks that it may cause movement disorders. Any adivice will be appreciated. thanks
hi there....i can't say i endorse the use of an anti-parkinsonian MAO-B inhibitor for increased sex drive...i also am wary of the metabolites - which are methamphetamine and amphetamine - given your past history with MDMA/speed, although it is not clear to me if, after dealkylation of methamphetamine, the amphetamine metabolite is further degraded via deamination...dietary restrictions for this MAO are not supposed to be a problem, but something to be aware of, as are the involuntary movements your doctor noted...in summary, i think that there are alternatives to what sounds like a drug with quite a few things you wouldn't want to be bothered by, and perhaps a selective NE reuptake inhibitor with weak affinity for dopamine receptors is worth looking into....just my opinion.....all the best, chemist
Posted by LastDyingWish on May 10, 2004, at 16:11:41
In reply to Re: question to chemist » LastDyingWish, posted by chemist on May 10, 2004, at 13:25:48
Posted by Sebastian on May 12, 2004, at 19:01:46
In reply to Re: question to chemist » LastDyingWish, posted by chemist on May 10, 2004, at 13:25:48
Dopamine is supposed to be best getting off of most drugs. Like cocaine, meth, nicotine,
Posted by chemist on May 12, 2004, at 19:28:43
In reply to Re: question to chemist, posted by Sebastian on May 12, 2004, at 19:01:46
> Dopamine is supposed to be best getting off of most drugs. Like cocaine, meth, nicotine,
....but dopamine is what produces the euphoria associated with these - and other - drugs. i was hesitant given the metabolic profile, in which (at least) 2 commonly abused intermediates are formed, and this poster had expressed some information which indicated substance abuse problems in the past. plus, lastdyingwish was/is loooking for a drug for prosexual effects: surrely there is a better choice than an MAO-B with methamhetamine and amphetamine as metabolic by-products......all the best, chemist
Posted by Sebastian on May 13, 2004, at 17:21:50
In reply to Re: question to chemist » Sebastian, posted by chemist on May 12, 2004, at 19:28:43
Acording to NIDA(National Institute of Drug Abuse). Dopamine is what you give someone who is trying to give up drugs, that are addictive. Dopamine is not addictive. The reason, pill medicine(which is not addictive, like zyprexa, for example), will fill the reward mecanisim, being dopamine receptors, so that they do not want the bad drugs. Also people who use illegal drugs, like the ones listed, have a depletion of dopamine in the brain, which is why they want the illegal drugs. Studies prove that when you give someone(or a lab rat) dopamine that they turn down the usage of illicit drugs. Thats why. I belive the drug used (or one of) in the tests was Selegelin.
Posted by chemist on May 13, 2004, at 17:30:40
In reply to Re: question to chemist, posted by Sebastian on May 13, 2004, at 17:21:50
> Acording to NIDA(National Institute of Drug Abuse). Dopamine is what you give someone who is trying to give up drugs, that are addictive. Dopamine is not addictive. The reason, pill medicine(which is not addictive, like zyprexa, for example), will fill the reward mecanisim, being dopamine receptors, so that they do not want the bad drugs. Also people who use illegal drugs, like the ones listed, have a depletion of dopamine in the brain, which is why they want the illegal drugs. Studies prove that when you give someone(or a lab rat) dopamine that they turn down the usage of illicit drugs. Thats why. I belive the drug used (or one of) in the tests was Selegelin.
thank you for the information, all the best, chemist
Posted by Sebastian on May 14, 2004, at 22:16:26
In reply to Re: question to chemist » Sebastian, posted by chemist on May 13, 2004, at 17:30:40
just to clarify. They do turn down usage, but not compleatly. Just want to make that point clear.
Ivan
Posted by chemist on May 14, 2004, at 23:40:27
In reply to Re: question to chemist, posted by Sebastian on May 14, 2004, at 22:16:26
> just to clarify. They do turn down usage, but not compleatly. Just want to make that point clear.
>
> Ivanyes, i am aware of that....thanks regardless, all the best, chemist
Posted by LastDyingWish on May 16, 2004, at 19:00:11
In reply to Re: question to chemist » Sebastian, posted by chemist on May 14, 2004, at 23:40:27
chemist,
My main concern is that iam twenty-two and my sex drive and also overall vitality is way down. I have been off drugs for 3 years and have no intention of using selegiline to fill the void. Iam very happy to be sober and have been accomplishing many things. I just want to feel the way i should feel, and i know that i do not.If not selegiline, what do you recommend ?
I would be using selegiline twice a week at 1 or 2 mg doses. Would i have to worry about the movement disorders at this dosage ? And also, Is this drug truly a nueroprotectant ? My thoughts are that if the drugs I used cause damage to certain areas of the brain, shouldnt these protectant properties be beneficial ?
Another question.. If dopamine and other catecholamines are the catalyst in hormone sectetion, and my nuerotransmitter system is off, could this be causing endocrine problems ?
Besides the libido, over the years my skin has become increasingly thin and dry, nothing helps.
Iam thinking it could be due to insufficent testosterone and growth hormone. There are claims that selegiline has the ability to raise these hormones to normal levels. I know its not that simple, thats why i need some advice.
Its hard to see through the propaganda on the internet, and that being the basis of my research makes figuring this out very overwhelming.
Any suggestions of clarifications would be of much help. thanks
Posted by chemist on May 16, 2004, at 22:32:04
In reply to Re: question to chemist, posted by LastDyingWish on May 16, 2004, at 19:00:11
> chemist,
> My main concern is that iam twenty-two and my sex drive and also overall vitality is way down. I have been off drugs for 3 years and have no intention of using selegiline to fill the void. Iam very happy to be sober and have been accomplishing many things. I just want to feel the way i should feel, and i know that i do not.
>
> If not selegiline, what do you recommend ?
>
> I would be using selegiline twice a week at 1 or 2 mg doses. Would i have to worry about the movement disorders at this dosage ? And also, Is this drug truly a nueroprotectant ? My thoughts are that if the drugs I used cause damage to certain areas of the brain, shouldnt these protectant properties be beneficial ?
>
> Another question.. If dopamine and other catecholamines are the catalyst in hormone sectetion, and my nuerotransmitter system is off, could this be causing endocrine problems ?
> Besides the libido, over the years my skin has become increasingly thin and dry, nothing helps.
> Iam thinking it could be due to insufficent testosterone and growth hormone. There are claims that selegiline has the ability to raise these hormones to normal levels. I know its not that simple, thats why i need some advice.
> Its hard to see through the propaganda on the internet, and that being the basis of my research makes figuring this out very overwhelming.
> Any suggestions of clarifications would be of much help. thankswhat is your gender, and have you seen a dermatologist to examine excema or perhaps some form of ichthyosis? let's get the full picture....it appears as if there are 2 issues that might be entirely orthogonal, and can be dealt with without adding fuel to the fire of the other...please inform, and also, have you had a cbc w/met panel recently? all the best, chemist
Posted by LastDyingWish on May 16, 2004, at 22:47:06
In reply to Re: question to chemist » LastDyingWish, posted by chemist on May 16, 2004, at 22:32:04
Iam a male, I have seen a dermatologist- no excema or ichthyosis, what is a cbc, met panel ?
Posted by chemist on May 16, 2004, at 23:21:06
In reply to Re: question to chemist, posted by LastDyingWish on May 16, 2004, at 22:47:06
> Iam a male, I have seen a dermatologist- no excema or ichthyosis, what is a cbc, met panel ?
Complete blood count (CBC) and a look at your metabolism, e.g., an immunoassay tarageted (usually) at t3 and t4.....also, have a urine test, let's look at electrolytes and urea/creatinine (although the creatinine can be determined from serum)....all the best, chemist
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