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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 17 of 17. This is the beginning of the thread.
Posted by Jaynee on May 1, 2004, at 23:54:23
I don't smoke, but I have bought some nicotine gum. I thought I would try it and see if I lose weight. Anyone else try this?
Posted by chemist on May 1, 2004, at 23:58:21
In reply to using nicorette gum for weight loss?, posted by Jaynee on May 1, 2004, at 23:54:23
> I don't smoke, but I have bought some nicotine gum. I thought I would try it and see if I lose weight. Anyone else try this?
chemist here....nicotine is one of the 10 most potent stimulants.....might work...taking any other meds? all the best, chemist
Posted by Jaynee on May 2, 2004, at 9:55:41
In reply to Re: using nicorette gum for weight loss? » Jaynee, posted by chemist on May 1, 2004, at 23:58:21
I am taking 10mg of Celexa most days and then I up it to 20mg about 10 days a month. Sometimes I take zopiclone to sleep. Lately claritin. Other than that I am taking Cod Liver Oil, Ashwagandha, and multi-vitamins with minerals(excluding iron).
Posted by Jaynee on May 2, 2004, at 10:22:26
In reply to using nicorette gum for weight loss?, posted by Jaynee on May 1, 2004, at 23:54:23
Just finished my first piece of gum and I feel like I just took 2mg of ativan. I can barely keep my head up to write this. Feel extremely stoned. Trying not to get freaked out about this, but feel really funky. Thought I was going to go for a jog, but instead I am going straight to bed.
Posted by linkadge on May 2, 2004, at 11:57:30
In reply to first piece of gum, feels like 2mg of ativan?, posted by Jaynee on May 2, 2004, at 10:22:26
I bought some gum as well the other day. I bought the 4mg gum. It was simultaiously stimulating and sedating. Nicotine increases gaba (ativan) as well as dopamine.
I felt very strange after chewing a piece. I found it made me feel very wierd.
Linkadge
Posted by Jaynee on May 2, 2004, at 13:10:02
In reply to Re: first piece of gum, feels like 2mg of ativan?, posted by linkadge on May 2, 2004, at 11:57:30
Glad to know I'm not the only one. I bought the 2mg. I think I will cut it in half and try that. I just got up from a 3 hour nap after chewing the nicorette gum. I am going to chew one before bed instead of taking the zopiclone. I did smoke ultra-lites in my early 20's for about 2 years and was so skinny the skinniest ever. So I thought I would try the nicotine gum to speed up my metobolism. But the gum affects me much differently than the smokes ever did. But I will not give up yet. I am determined to chew the whole pack, especially since it is expensive.
Posted by Sad Panda on May 2, 2004, at 13:32:15
In reply to using nicorette gum for weight loss?, posted by Jaynee on May 1, 2004, at 23:54:23
> I don't smoke, but I have bought some nicotine gum. I thought I would try it and see if I lose weight. Anyone else try this?
>
>Hi Jaynee,
Is it really worth clogging up your arteries so you can lose weight? The only good thing I have ever read about nicotine is that it improved memory a little. Everything else I have ever seen says it's just really bad news. I'm pretty sure I spiraled into depression after giving up smoking, because quitting ciggies was like loosing a best friend, but even if I knew that ingesting nicotine would cure my depression I still wouldn't do it. It's just an evil nasty drug.
Cheers,
Panda.
Posted by Jaynee on May 2, 2004, at 14:21:21
In reply to Re: using nicorette gum for weight loss? » Jaynee, posted by Sad Panda on May 2, 2004, at 13:32:15
Posted by chemist on May 2, 2004, at 14:35:27
In reply to Re: using nicorette gum for weight loss? » Jaynee, posted by Sad Panda on May 2, 2004, at 13:32:15
> > I don't smoke, but I have bought some nicotine gum. I thought I would try it and see if I lose weight. Anyone else try this?
> >
> >
>
> Hi Jaynee,
>
> Is it really worth clogging up your arteries so you can lose weight? The only good thing I have ever read about nicotine is that it improved memory a little. Everything else I have ever seen says it's just really bad news. I'm pretty sure I spiraled into depression after giving up smoking, because quitting ciggies was like loosing a best friend, but even if I knew that ingesting nicotine would cure my depression I still wouldn't do it. It's just an evil nasty drug.
>
> Cheers,
> Panda.
>
>
>
hi all, chemist here....turns out i work extensively with nicotine, please allow me to share some stuff.....first of all, the human neuronal nicotine receptor is structurally homologous to GABA_{A}, GABA_{C}, glutamate and glycine receptors, and the 5-HT_{3} (serotonin) receptor. there was an earlier post in which it was stated that nicotine possesses GABAnergic activity (likening it to ativan): this is incorrect, as the beta4 subunit of the human neuronal nicotine receptor has the highest sequence identity with the alpha1 subunit of GABA_{A,C}, yet the 2 arrangements of subunits in the human neuronal nicotine receptors to which nicotine binds most tightly are (alpha7)_{5} and (alpha4)_{2}(beta2)_{3}. so, no-go on anxiolytic properties of nicotine via a mechanism like that of the benzodiazepenes. there is evidence that the second form (containing beta2) is implicated in dopamine regulation: this was correctly stated. as for memory enhancement: also correct, and it is worth noting that nootropics target the neuronal nicotine receptors (alzheimer's and parkinson's being wrthy of mention). nicotine is also a proven remedy for alleviating symptoms of schizophrenia. this is why many schizophrenics smoke: they are self-medicating. in the end: there are very little if not any data that would support anxiolytic effects of nicotine *in the neurological* sense (i leave this open noting that nicotine is a brochodilator and, upon inhaling/ingestion, perfusion of oxygen into blood occurs). and yes, smoking is a bad idea, but i will not pass judgement on that one, we all have our crosses to bear....all the best, chemist
Posted by linkadge on May 2, 2004, at 15:42:09
In reply to Re: using nicorette gum for weight loss? » Sad Panda, posted by chemist on May 2, 2004, at 14:35:27
Nicotine also seems to help people with tourretts (am I right on that on chemist ??). Anyhow, is chewing nicotine gum going to clog your arteries ??
How could this happen ??
Linkadge
Posted by linkadge on May 2, 2004, at 15:45:01
In reply to Re: using nicorette gum for weight loss?, posted by linkadge on May 2, 2004, at 15:42:09
I also read one study that said that nicotine ingestion decreased the responsivness of the presynaptic serotonin 1a autoreceptor. This is congruent with other antidepressant treatments.
Nicotine is also effective in the forced rat swim test.Linkadge
Posted by chemist on May 2, 2004, at 16:33:33
In reply to Re: using nicorette gum for weight loss?, posted by linkadge on May 2, 2004, at 15:42:09
> Nicotine also seems to help people with tourretts (am I right on that on chemist ??). Anyhow, is chewing nicotine gum going to clog your arteries ??
>
> How could this happen ??
>
> Linkadge
hi there....yes on tourette's, out in the cold on the arteries thing.....all the best, tjm
Posted by chemist on May 2, 2004, at 16:34:46
In reply to Re: using nicorette gum for weight loss?, posted by linkadge on May 2, 2004, at 15:45:01
> I also read one study that said that nicotine ingestion decreased the responsivness of the presynaptic serotonin 1a autoreceptor. This is congruent with other antidepressant treatments.
> Nicotine is also effective in the forced rat swim test.
>
>
>
> Linkadge
could you provide to me the leterature citation? thanks....all the best, chemist
Posted by Sad Panda on May 2, 2004, at 17:47:35
In reply to Re: using nicorette gum for weight loss?, posted by linkadge on May 2, 2004, at 15:42:09
> Anyhow, is chewing nicotine gum going to clog your arteries ??
>
> How could this happen ??
>
> Linkadge
>
>Hi Linkadge,
Nicotine is a vasoconstrictor & raises heart rate & blood pressure. Nicotine also causes artery wall damage which leads to Arteriosclerosis. Sucking down smoke might give you cancer and emphysema, but it's nicotine that causes all sorts of vascular problems which leads to heart attacks, strokes & having gangrenous limbs cut off due to poor circulation. The leaflet that comes with the gum tells you to quit after 6 months too, you would think if nicotine was harmless that nicotine gum & patch makers would engourage you to use their product indeffinately.
Cheers,
Panda.
Posted by Jaynee on May 2, 2004, at 21:24:51
In reply to Re: using nicorette gum for weight loss? » linkadge, posted by Sad Panda on May 2, 2004, at 17:47:35
Posted by Sad Panda on May 3, 2004, at 3:00:06
In reply to blood pressure? check out this link, posted by Jaynee on May 2, 2004, at 21:24:51
That's just one person & I would say he's having a pardoxial reaction. In the same thread here http://www.dr-bob.org/babble/19981101/msgs/1401.html "after habitual use it seems to have no effect" My experience & the experience of every smoker I ever spoke with would say the same thing, there is no high or rush from it after you have used it for awhile, just addiction. IMHO, there is no drug around that is more addictive & yet offers so little in terms of positive effect, the fact that smoking is still around today is teastment to just how evil this drug is.
Cheers,
Panda.
Posted by almondjoy on May 4, 2004, at 0:37:57
In reply to Re: blood pressure? check out this link » Jaynee, posted by Sad Panda on May 3, 2004, at 3:00:06
> That's just one person & I would say he's having a pardoxial reaction. In the same thread here http://www.dr-bob.org/babble/19981101/msgs/1401.html "after habitual use it seems to have no effect" My experience & the experience of every smoker I ever spoke with would say the same thing, there is no high or rush from it after you have used it for awhile, just addiction. IMHO, there is no drug around that is more addictive & yet offers so little in terms of positive effect, the fact that smoking is still around today is teastment to just how evil this drug is.
>
> Cheers,
> Panda.
>tru dat
d
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