Psycho-Babble Medication Thread 335137

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Question about MAO inhibitors

Posted by linkadge on April 11, 2004, at 9:25:50

Does anyone know if a selective MAO-A inhibitor would require the dietary restrictions like parnate/nardil. Which of the two enzymes is responsable for the hypotensive reaction.


Linkadge

 

Re: Question about MAO inhibitors

Posted by King Vultan on April 11, 2004, at 9:55:57

In reply to Question about MAO inhibitors, posted by linkadge on April 11, 2004, at 9:25:50

> Does anyone know if a selective MAO-A inhibitor would require the dietary restrictions like parnate/nardil. Which of the two enzymes is responsable for the hypotensive reaction.
>
>
> Linkadge


It's a hypertensive reaction actually, and it is the MAO-A enzyme that is the problematic one. However, if the MAOI is a reversible MAO-A inhibitor like moclobemide, an MAOI diet is not required. This is a moot point for US residents, though, as this drug is not available in the United States.

Todd

 

Re: Question about MAO inhibitors

Posted by SLS on April 11, 2004, at 13:17:06

In reply to Re: Question about MAO inhibitors, posted by King Vultan on April 11, 2004, at 9:55:57

Tyramine hypertensive reactions have been reported with moclobemide. It is recommended that no more than 50mg be consumed at any one meal.


- Scott


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