![[dr. bob]](/dr-bob-sm.gif)
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 3 of 3. This is the beginning of the thread.
Posted by Canyon on March 27, 2004, at 0:23:09
Hi, I am Bipolar-One. My relatively high doses of lithium (1000mg) and Moclobemide (600mg) do not seem to be fostering stability. I have had two 2+ month-long depressive episodes and possibly one 2+ month-long hypomanic episodes in the last 12 months. I have been on this med combination for about 4 years now with a similar trend each year. Any ideas on better med combiniations? Mental heath care in New Zealand is of the post-catastrophic variety, so I am reaching out. Thanks, Canyon
Posted by Keith Talent on March 27, 2004, at 1:45:00
In reply to Lithium/Moclobemide not working for Bipolar, posted by Canyon on March 27, 2004, at 0:23:09
What matters with lithium is the concentration in the blood, not the dose. What was your concentration the last time it was measured? I tried moclobemide once for depression at 900mg/day. It was absolutely useless. I suspect that's why it's never been approved by the US FDA.
Posted by Canyon on March 27, 2004, at 14:14:26
In reply to Re: Lithium/Moclobemide not working for Bipolar, posted by Keith Talent on March 27, 2004, at 1:45:00
> What matters with lithium is the concentration in the blood, not the dose. What was your concentration the last time it was measured? I tried moclobemide once for depression at 900mg/day. It was absolutely useless. I suspect that's why it's never been approved by the US FDA.
Thanks for that. My measured concentrations have consistantly been in the 0.8 and 1.2 mmol/L range, usually between 0.8-1.0 mmol/L when measured 12 hours out from ingestion. Interesting about Moclobemide. I will look at switching AD.
This is the end of the thread.
Psycho-Babble Medication | Extras | FAQ
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.org
Script revised: February 4, 2008
URL: http://www.dr-bob.org/cgi-bin/pb/mget.pl
Copyright 2006-17 Robert Hsiung.
Owned and operated by Dr. Bob LLC and not the University of Chicago.