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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 3 of 3. This is the beginning of the thread.
Posted by Dinah on March 25, 2004, at 8:28:42
In reply to nasal administration, posted by appadoo on March 25, 2004, at 5:24:14
Originally posted by appadoo 3/25/04
> I am been diagnosed as having ADHD as an adult about over 6 months ago.My doctor has increased my dosage of dexemphatamines from 20mg a day to 30mg.inorder to get through the entire day.Please understand that in Australia we do no have the long acting stimulantes available becuase there is no market for them.The only medical treatment we have is dexemphatamines generic and ritalin.My question is that since I am limited in my choices i want the medication to work for me at the optimum level.I have tried to increase the bioavailability by either administrating the drug by the buccal route and/or administer it to the mucous membrane via nose.I sometimes do this so its not destroyed by the GI tract.Is this a good idea or am I just wasting the medicine since it has no impact and doesn't get through its intented site.
> Should I just take it as its intented orally and put up with it being destroyed from what I have read 40-50% of the time by the liver.
> By the way I really notice no difference when I the unorthodox route however I only do it 1 out 6 times in the day and the rest of the time follow prodical.
>
> Your imput will be appreciated.
Posted by Bill LL on March 25, 2004, at 9:41:30
In reply to Re: nasal administration » appadoo, posted by Dinah on March 25, 2004, at 8:28:42
I saw this on www.ravesafe.org :
"There are numerous reports in medical journals about permanent and irreversible lung tissue damage related to the injection of crushed Ritalin tablets. When snorted, the salts used in Ritalin tablets turn into hydrochloric acid when they come into contact with moisture. While this is not a problem in the stomach, in the nasal passages the acid can "burn" the delicate nasal tissues, resulting in open sores, nose bleeds, and possibly in deterioration of the nasal cartilage."
Posted by Keith Talent on March 27, 2004, at 7:11:46
In reply to Re: nasal administration, posted by Bill LL on March 25, 2004, at 9:41:30
Well, obviously the dose must be enough to take account of the "first pass" metabolism (when it's absorbed from the gut). It sounds like your dose is too low. You must tell your psychiatrist this.
This is the end of the thread.
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