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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 11 of 11. This is the beginning of the thread.
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Posted by HappyGirl on February 7, 2004, at 0:13:13
In reply to xyrem or depakote for insomnia? Feedback please!, posted by allye on February 6, 2004, at 16:54:43
Hi:
Depakote is mood-stabilizer. Lithium you've been on already is also 'Mood-stabilizer.' I don't think you need *two* m.s. same time. Rather, Lamical might be a good choice, but skin-problem is one of very annoying problem, then before asking your pdoc., you need to think about a lot about this. Besides this, Lamictal has both mood-stabilizer and 'good' anti-dep. effect. I never been on, ... but seems very good med.
In regard to your current weight issue is, I suspect, two meds., Lithium and Zoloft. Those two gives you a good appetite, ... in my knowledge.
xyrem about which you're asking, ... I have NEVER heard of. But, since you're looking for sleeping med., then a tiniest dosage of 'Seroquel' might be a good choice, ... or 'Trazodone' that is milder form of AD, but work for insomnia, unless your insomnia is serious form.
Try to ask your pdoc. on this regard, because sleep-good is one very crucial recovery on any of M.I. you have.
H.G.
Posted by scott-d-o on February 7, 2004, at 2:16:29
In reply to Re: xyrem or depakote for insomnia? Feedback please!, posted by HappyGirl on February 7, 2004, at 0:13:13
> Hi:
> Depakote is mood-stabilizer. Lithium you've been on already is also 'Mood-stabilizer.' I don't think you need *two* m.s. same time. Rather, Lamical might be a good choice, but skin-problem is one of very annoying problem, then before asking your pdoc., you need to think about a lot about this. Besides this, Lamictal has both mood-stabilizer and 'good' anti-dep. effect. I never been on, ... but seems very good med.
> In regard to your current weight issue is, I suspect, two meds., Lithium and Zoloft. Those two gives you a good appetite, ... in my knowledge.
> xyrem about which you're asking, ... I have NEVER heard of. But, since you're looking for sleeping med., then a tiniest dosage of 'Seroquel' might be a good choice, ... or 'Trazodone' that is milder form of AD, but work for insomnia, unless your insomnia is serious form.
> Try to ask your pdoc. on this regard, because sleep-good is one very crucial recovery on any of M.I. you have.
> H.G.
i'm sure you've heard of xyrem, however you probably know it as GHB or the so-called "date-rape" drug. the fda approved it for treatment of narcolepsy in 2002..it's funny to observe the politics between the DEA and the FDA. On one hand, you have GHB classified as a schedule I substance, (high abuse potential, no medical value, like heroin, LSD, etc.), however, pharmaceutical ghb is now a schedule III substance (lower abuse potential, medical use accepted.) doesn't make much sense, does it? then again, neither do any of the drug laws in this country.
scott
Posted by Chairman_MAO on February 7, 2004, at 10:37:49
In reply to Re: xyrem or depakote for insomnia? Feedback plea » HappyGirl, posted by scott-d-o on February 7, 2004, at 2:16:29
I'd like someone to produce to me one iota of evidence that GHB alone is implicated in *ANY* date rape.
Posted by HappyGirl on February 7, 2004, at 12:14:34
In reply to Re: xyrem or depakote for insomnia? Feedback plea » HappyGirl, posted by scott-d-o on February 7, 2004, at 2:16:29
Hi scott-d-o:
Thanks for a GOOD explanation on this regard. I heard that 'date Drug,' but the name for this, ... I didn't know. Because, practically I never interested in reading those articles.
In my VERY personal 'guess,' there is no or very few of pdocs. prescribes this med., because of the nature of drug. But, ... who knows, ... If nothing helping on insomnia, then probably as a last resort, there might rx as for 'SPECIAL' reason. But, ... again, as for my pdoc., I VERY MUCH doubt about this form of med., because he's pretty stern and conservative type of pdoc. whom you could meet at the very professional medical setting, as seeing many different diplomas on the wall behind the big-chair he's sitting.
Still, ... then in my opinion, there is very safe to ask 'Seroquel' or 'Trazodone.' Oh, ... in my case, Zyprexa 5mg. before going to the bed. is a tremendous effect on my sleep, ... actually so sound that I hardly waking up unless a big 'BANG' on the wall next room.
H.G.
Posted by scott-d-o on February 7, 2004, at 13:39:55
In reply to Re: date rape drug, posted by Chairman_MAO on February 7, 2004, at 10:37:49
> I'd like someone to produce to me one iota of evidence that GHB alone is implicated in *ANY* date rape.
not sure about that, but it is true that at higher doses it can easily put someone into a comatose state, meaning that they are sleeping and it is impossible to wake them up for about 4-5 hours. so I guess it's almost like necrophilia in a sense.. I've seen both alcohol and benzos do the same thing to people, but supposedly the difference in dosage between a euphoric high and comatose sleep is very small with GHB.
scott
Posted by Chairman_MAO on February 7, 2004, at 14:08:15
In reply to Re: date rape drug » Chairman_MAO, posted by scott-d-o on February 7, 2004, at 13:39:55
> not sure about that, but it is true that at higher doses it can easily put someone into a comatose state, meaning that they are sleeping and it is impossible to wake them up for about 4-5 hours. so I guess it's almost like necrophilia in a sense.. I've seen both alcohol and benzos do the same thing to people, but supposedly the difference in dosage between a euphoric high and comatose sleep is very small with GHB.
Exactly what I was thinking. Therefore, no single drug deserves the designation of "date rape drug". A few milligrams of alprazolam in a drink would have the same short-lived (and potentially fatal) incapacitating effect--with less chance of being detected by the victim than a few grams of salty-tasting GHB. Hell, clonazepam is MINTY. If a drug is to be designated "the date rape drug" based upon the number of unwilling participants in sexual acts it produces, there is only one choice: alcohol.
We should, as a society, stop worrying about the drugs and demonizing them for our ills and start asking the real questions, such as "HOW on EARTH could anyone ENJOY a sexual encounter with an unconscious person!??!?!?!?!"
The fact that raping someone carries less of an aggregate prison sentence than possession of GHB did when it was schedule I makes me want to renounce my citizenship.
Posted by Karen Moore on February 7, 2004, at 14:36:38
In reply to Re: xyrem or depakote for insomnia? Feedback please!, posted by HappyGirl on February 7, 2004, at 0:13:13
> Depakote is mood-stabilizer. Lithium you've been on already is also 'Mood-stabilizer.' I don't think you need *two* m.s. same time.
> H.G.Actually, for a significant minority of rapid cycling treatment resistant bps, it may take as many as *three* mood-stabilizers. Unlike say the SSRI class, stabilizers are a very diverse class of drugs, most have totally different mechanisms of action. Therefore combining two or three can have synergistic effects. (Whereas combining two SSRI's rarely makes much sense/difference).
In the short term your insomnia may not improve on stabilizers. But in the long term, as your system comes back online, your sleep patterns will hopefully settle back to normal...
Posted by HappyGirl on February 7, 2004, at 16:05:19
In reply to Re: xyrem or depakote for insomnia? Feedback pleas » HappyGirl, posted by Karen Moore on February 7, 2004, at 14:36:38
Hi Karen M.:
That's correct. I agree with you in regard to M.S. effectiveness. It could be used two or more M.S. at a time, like 'add-on' Neurontin, Topamax and the others.
However, in my opinion, Depakote and Lithium is NOT a good match. Actually, I went through this, ... I was on both, Lithium and Depakote at the beginning of my dx. Bipolar. However, in my VERY personal experience, this combo. did NOT help me, ... rather practically seems I was just on one of med. that was on Lithium only. The effectiveness of Depakote was so faint, AFTER Lithium was added. However, I understand/know that everyone reacts differently on different med., then I can NOT be sure to say about this, the effectiveness when on two M.S.
H.G.
Posted by Karen Moore on February 7, 2004, at 16:28:23
In reply to Re: xyrem or depakote for insomnia?/Karen Moore, posted by HappyGirl on February 7, 2004, at 16:05:19
Thanks HG. This is quite helpful, I have recently considered trying the combo of Li and Dep. But I think my next test will be Dep. and a Ca channel blocker like Nimodipine. Have you ever tried that combo?
KM> Hi Karen M.:
> That's correct. I agree with you in regard to M.S. effectiveness. It could be used two or more M.S. at a time, like 'add-on' Neurontin, Topamax and the others.
> However, in my opinion, Depakote and Lithium is NOT a good match. Actually, I went through this, ... I was on both, Lithium and Depakote at the beginning of my dx. Bipolar. However, in my VERY personal experience, this combo. did NOT help me, ... rather practically seems I was just on one of med. that was on Lithium only. The effectiveness of Depakote was so faint, AFTER Lithium was added. However, I understand/know that everyone reacts differently on different med., then I can NOT be sure to say about this, the effectiveness when on two M.S.
> H.G.
>
Posted by HappyGirl on February 7, 2004, at 18:12:53
In reply to Re: Combos of M. Stabilizers » HappyGirl, posted by Karen Moore on February 7, 2004, at 16:28:23
Hi Karen M.:
Well, .... I never experienced the med. about you're talking. As for a Bp person, I am pretty resistent to all kind of med., then 'trial and error' did not happen often although my ex-pdoc. tried many M.S. on me for her study/research(?). Then, I have NO good knowledge/opinion other than regular/ordinary Bp and AP meds.
I'm sorry to hear/read that you had a bad reaction to Zyprexa, ... then as a fellow Bp, I am very sympatheticm to your situation, as seeing many of Bp getting 'relief' from taking Zyprexa. But, ... you are well tolerable to Seroquel, ... from there, taking a higher dosage, hopefully you can get good result.
H.G.
This is the end of the thread.
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