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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 7 of 7. This is the beginning of the thread.
Posted by jpmjcem on February 4, 2004, at 9:59:12
I want to get off of Effexor XR and try Buspar. Does anyone have any comments about Buspar??
Posted by Chairman_MAO on February 4, 2004, at 10:25:29
In reply to ANYONE TRIED BUSPAR FOR GAD?, posted by jpmjcem on February 4, 2004, at 9:59:12
>I want to get off of Effexor XR and try Buspar. Does anyone have any comments about Buspar??
Yes, myself, some doctors I've talked to, and others think that it's the most expensive placebo available. Other people swear by it. Unless your GAD is mild, it probably won't work. Augmenting your Effexor with buspar could possibly give you better results than either alone.
Posted by Joy on February 4, 2004, at 10:43:37
In reply to Re: ANYONE TRIED BUSPAR FOR GAD?, posted by Chairman_MAO on February 4, 2004, at 10:25:29
My understanding is that Buspar generally only works added to an antidepressant for GAD. It should be added very gradually and don't expect results for 3 or 4 weeks at least. By itself it helps very few, but it helps quite a few people if their antidepressant is the right one for them.
Joy
Posted by crazychickuk on February 4, 2004, at 12:00:06
In reply to Re: ANYONE TRIED BUSPAR FOR GAD?, posted by Joy on February 4, 2004, at 10:43:37
is it good with remeron?
Posted by jpmjcem on February 4, 2004, at 12:21:41
In reply to Re: ANYONE TRIED BUSPAR FOR GAD?with remeron?, posted by crazychickuk on February 4, 2004, at 12:00:06
I have severe Generalized Anxiety so I guess it would be better to stay on teh Effexor XR and wait until I can go to a doc again.
Posted by Mimi on February 4, 2004, at 16:48:28
In reply to ANYONE TRIED BUSPAR FOR GAD?, posted by jpmjcem on February 4, 2004, at 9:59:12
Posted by zeugma on February 4, 2004, at 19:10:05
In reply to Re: ANYONE TRIED BUSPAR FOR GAD?, posted by Chairman_MAO on February 4, 2004, at 10:25:29
My personal theory is that buspar works a lot better when combined with a noradrenergic-type med (high-dose Effexor, Strattera, TCA) because of its metabolite which is an alpha-2 antagonist and boosts NE transmission. Remeron with effexor is called 'California rocket fuel' and buspar might make a similarly potent combination. It seems that buspirone can actually interfere with an SSRI's effect on 5-HT even as it improves sexual dysfunction (it is a partial agonist and can either raise or lower serotonin levels, depending on whether the levels are high or low to begin with. On an SSRI they would naturally be high.) I doubt any drug company will test this theory now that it's off patent but from the small sample here (n=2) it seems to have some validity.
This is the end of the thread.
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