Psycho-Babble Medication Thread 299966

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Substance-P Antagonists - the next BIG thing??

Posted by bipolarspectrum on January 12, 2004, at 18:45:13

Hello,
I've been researching substance P antagonists and they seem promising in a placebo-controlled comparision to Paxil... Assuming they are available, has anyone tried a substance p antagonist????

Re: Substance-P Antagonists - the next BIG thing??

Posted by rod on January 13, 2004, at 15:57:57

In reply to Substance-P Antagonists - the next BIG thing??, posted by bipolarspectrum on January 12, 2004, at 18:45:13

> Hello,
> I've been researching substance P antagonists and they seem promising in a placebo-controlled comparision to Paxil... Assuming they are available, has anyone tried a substance p antagonist????
>

well yes. 1 time I guess. Whatever it was, Paxil or Mk869?(number right?). i woke up in the middle of the night and was paralysed, got a panik attack and so on. I will never take that crap again.
My doctor told me that Merk stoped all further development of their Substance-P antagonists, because they just dont work. My doctor conducted 2 Double blind Comparative Studies (Paxil vs. SP-Antag.). Both without success.

Re: Substance-P Antagonists - the next BIG thing??

Posted by bipolarspectrum on January 13, 2004, at 17:01:09

In reply to Re: Substance-P Antagonists - the next BIG thing??, posted by rod on January 13, 2004, at 15:57:57

> well yes. 1 time I guess. Whatever it was, Paxil or Mk869?(number right?). i woke up in the middle of the night and was paralysed, got a panik attack and so on. I will never take that crap again.
> My doctor told me that Merk stoped all further development of their Substance-P antagonists, because they just dont work. My doctor conducted 2 Double blind Comparative Studies (Paxil vs. SP-Antag.). Both without success.
>

Rod,
Thanx for the reply... Say it aint so! I wondered why there hasnt been more research upon substance P antagonists in the last couple years...

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