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Dr. Bob is Robert Hsiung, MD,
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Posted by theo on September 21, 2003, at 15:19:06
In reply to re: Theo » theo, posted by lil' jimi on September 21, 2003, at 14:28:02
Thanks for the time you took posting. I actually took 2.5mg Lex about noon and after a few days will take 5mg to see what happens. At least if the Lex doesn't work for me I know it won't be to difficult for me to just stop taking as it would be with the Paxil, which luckily wasn't to bad but I definitly felt spun for a few days after discontinuing it. I know it's trial and error but that 6 week trial period can seem like forever can't it! Although I only took 2.5mg Lex, I can feel the med but no nausea and tiredness at all where as before starting with 10mg I was anxious and nauseated. In my research I did find this graph interesting. Look at the effectiveness of Lex at 5mg vs 10mg. 5mg better response than 10mg, then back up when increased to 20mg.
http://images.medscape.com/pi/editorial/cmecircle/2003/2546/images/kent/slide20.gif
Posted by lil' jimi on September 21, 2003, at 16:07:02
In reply to re: Theo » lil' jimi, posted by theo on September 21, 2003, at 15:19:06
hi Theo,
> Thanks for the time you took posting. >
you're welcome ... ... what the heck ... it doesn't seem anyone's using the thread much now ... ... so they shouldn't mind, anyway ...
it's my pleasure ...
> I actually took 2.5mg Lex about noon and after a few days will take 5mg to see what happens. At least if the Lex doesn't work for me I know it won't be to difficult for me to just stop taking as it would be with the Paxil, which luckily wasn't too bad but I definitly felt spun for a few days after discontinuing it. I know it's trial and error but that 6 week trial period can seem like forever can't it! >
excellent ... ... and it does seem like eternity waiting for a med to get our system stabilized ... ... but it is a positive that you're expectaions are prepared ... ...
> Although I only took 2.5mg Lex, I can feel the med but no nausea and tiredness at all where as before starting with 10mg I was anxious and nauseated. >
way good !!
> In my research I did find this graph interesting. Look at the effectiveness of Lex at 5mg vs 10mg. 5mg better response than 10mg, then back up when increased to 20mg.
>
> http://images.medscape.com/pi/editorial/cmecircle/2003/2546/images/kent/slide20.gifthis graph is a surprise ... ... implying as it does that 5mg is more effective for SA than 10 mg ... ... thank you for such valuable information ... ... would you share the url for the article it came with please ... thanks
my best idea for you (took me posting this much to come up with a good one!):
post to the main pBabble thread with a subject line like, "Wellbutrin-Lexapro combo users' reports wanted!" ... and then in the post ask for any experiences with well-lex and well-pax combos ...
... the main board won't be so lexapro specific ... and lots more folks will be able to take noitce ... bigger audience = more feedback ...
good luck!
~ jim
Posted by lil' jimi on September 21, 2003, at 16:39:02
In reply to Re: PAXIL toLexapro and back to Paxil, posted by leedsman on September 20, 2003, at 18:45:50
hi leedsman,
> I was taking Lexapro for 6 weeks and really did not have much success , I started getting really bad necka nd muscle pain, I talked to my pdoc and she asked me if I wanted to take Wellbutrin along with Lexapro to give it a boost, but what I have read on the psycho-babble, it makes you high like you are on marijuana or something. >
hadn't heard that one
> I thought I would just try Paxil again and am taking 25mg Paxil CR for 3-4 weeks to see if it helps, can you take Wellbutrin with Paxil also? >
from what Theo was just posting, that answwr seems to be yes ...
> I had really good results with regular Paxil, for 5 years, I know there is a time release with the CR, but it's still the same right? >well, i'd presume so, but i do not know ... ... the manufacturer's web site should make that clear ...
> What if I get off Paxil after a week can I start right on the Lexapro again or should I wean down. >
i don't have any positive paxil experience to know one way or the other ... ... except that paxil withdrawals are so notorious ... but one week ? ... beats me ... another post for the main board where there will be more folks with paxil experience, maybe ?
> I appreciate your advice and I hope Lexapro is working for all of you >
thanks ... best to you, leedsman ...
... come and visit anytime ... ... it'd be great to hear how you are doing there ...
TAKE CARE !
~ jim
Posted by lil' jimi on September 21, 2003, at 17:00:50
In reply to Anxiety - Jaw Clenching - Weight Gain - What's Up?, posted by PHV on September 20, 2003, at 22:30:58
hi Patty,
you wrote:
....
> Thanks for listening to me vent . . .
>
> Pattysorry to hear things have taken this turn for you there ...
you have just volunteered to be in the post-adjustment SEs group ... with Galkeepinon, Sussus, Banab and maybe Mariposa ... ... Mariposa has yet to response to her candidacy ... ...
it would be appreciated here if you could share with us your pdoc's reactions to your new situation ... ... good doc to provide the benzos for your anxieties ...
thanks for your post(s) ... ... and please keep us posted!
TAKE CARE !!
~ jim
Posted by theo on September 21, 2003, at 17:50:31
In reply to re: Theo » theo, posted by lil' jimi on September 21, 2003, at 16:07:02
There's 15 or so slides in this presentation. I believe slide 20 is the graph I sent you and the info explaining the graph will be under this slide. If you have time I would view the entire deal, some pretty interesting info.
http://www.medscape.com/viewarticle/458647_15?WebLogicSession=P24pQkGWxo3Dw6YdttqMpONZZrpWDrFRXV136u1I2ef5iawzF3aQ|-3360746919023192434/184161393/6/7001/7001/7002/7002/7001/-1
Posted by lil' jimi on September 21, 2003, at 20:00:43
In reply to re: lil' jimi, posted by theo on September 21, 2003, at 17:50:31
hi Theo,
> There's 15 or so slides in this presentation. I believe slide 20 is the graph I sent you and the info explaining the graph will be under this slide. If you have time I would view the entire deal, some pretty interesting info.
>
> http://www.medscape.com/viewarticle/458647_15?WebLogicSession=P24pQkGWxo3Dw6YdttqMpONZZrpWDrFRXV136u1I2ef5iawzF3aQ|-3360746919023192434/184161393/6/7001/7001/7002/7002/7001/-1
... i've only just started this article at
http://www.medscape.com/viewarticle/458647_15
... but i wanted to share it here even before i could finish it ...i would enjoy any of our threadsters' reaction(s) to Dr. Kent's paper ...
and thanks to Theo for providing this information
~ jim
p.s. accessing the paper requires registration with medscape ... which is not any more painful than registration here .
~ j
Posted by lil' jimi on September 21, 2003, at 20:18:54
In reply to SSRIs and Beyond, posted by lil' jimi on September 21, 2003, at 20:00:43
hello everyone,
here are some of the basics about lexapro we can get from online ... ... of particular interest, we have the list of side effects ...
anybody's presciber mention even half of these?
anyone get any of this lowdown from their pharmacist ?have a good week,
~ jimthis is from http://www.medicinenet.com/escitalopram/article.htm
GENERIC NAME: escitalopram
BRAND NAME: Lexapro
DRUG CLASS AND MECHANISM: Escitalopram is an oral drug that is used for treating depression. It is an antidepressant. It works by affecting neurotransmitters in the brain, the chemical messengers that nerves use to communicate with one another. Neurotransmitters are made and released by nerves and then travel to other nearby nerves where they attach to receptors on the nerves. Some neurotransmitters that are released do not bind to receptors and are taken up by the nerves that produced them. This is referred to as "reuptake."Many experts believe that an imbalance of neurotransmitters is the cause of depression. Escitalopram prevents the reuptake of one neurotransmitter, serotonin, by nerves, an action which results in more serotonin in the brain to attach to receptors. Chemically, escitalopram is very similar to citalopram. Both are in the class of drugs called selective serotonin reuptake inhibitors (SSRIs), a class that also includes fluoxetine (Prozac), paroxetine (Paxil) and sertraline (Zoloft).
PRESCRIPTION: Yes
GENERIC AVAILABLE: No
PREPARATIONS: White to off-white, round tablets of 5, 10, and 20 mg.
STORAGE: Escitalopram tablets should be stored at controlled room temperature, 59-86°F (15-30°C.)
PRESCRIBED FOR: Escitalopram is used to treat depression. Drugs in the SSRI class also have been studied in persons with obsessive-compulsive disorders, general anxiety disorders, and panic disorders.
DOSING: The usual starting dose of escitalopram is 10 mg once daily. Benefit may not be seen until treatment has been given for up to 4 weeks. Escitalopram can be taken with or without food. Older and younger persons require similar doses.
DRUG INTERACTIONS: All SSRIs, including escitalopram, should not be taken together with any drugs of the MAO (mono-amine oxidase) inhibitor-class of antidepressants, for example, isocarboxazid (Marplan), phenelzine (Nardil), tranylcypromine (Parnate), and procarbazine (Matulane). Such combinations may lead to confusion, high blood pressure, high fevers, tremor or muscle rigidity, and increased activity. This same type of interaction also may occur with selegiline (Eldepryl), fenfluramine (Pondimin), and dexfenfluramine (Redux). Tryptophan can cause headaches, nausea, sweating, and dizziness when taken with any SSRI. At least 14 days should elapse after discontinuing escitalopram before starting a MAO inhibitor.
PREGNANCY: The safety of escitalopram during pregnancy and lactation has not been established. Therefore, escitalopram should not be used during pregnancy unless, in the opinion of the physician, the expected benefits to the patient outweigh the possible hazards to the fetus.
NURSING MOTHERS: Escitalopram is excreted in human milk. Escitalopram should not be given to nursing mothers unless, in the opinion of the physician, the expected benefits to the patient outweigh the possible hazards to the child.
SIDE EFFECTS: The most commonly-noted side effects associated with escitalopram are agitation or restlessness, blurred vision, diarrhea, difficulty sleeping, drowsiness, dry mouth, fever, frequent urination, headache, indigestion, nausea, increased or decreased appetite, increased sweating, sexual difficulties (decreased sexual ability or desire, ejaculatory delay), taste alterations, tremor (shaking), weight changes. Although changes in sexual desire, sexual performance and sexual satisfaction often occur as a result of depression itself, they also may be a consequence of the drugs used to treat depression. In particular, about one in 11 men given escitalopram report difficulties experiencing ejaculation.
Some patients may experience withdrawal reactions upon stopping SSRI therapy. Symptoms may include dizziness, tingling, tiredness, vivid dreams, irritability, or poor mood. In order to avoid these symptoms, the dose of SSRI can be slowly reduced instead of abruptly stopped.
Posted by oldhand on September 21, 2003, at 20:41:26
In reply to SSRIs and Beyond, posted by lil' jimi on September 21, 2003, at 20:00:43
Hi Theo and lil jimi!
I just got WellbutrinXL, 150mg added to my Lexapro 20mg. It has not been a week yet so I hesitate to try to define any changes.
I told the psychiatrist that though I felt ok on the Lex, I was just not feeling great, noting that one cannot be happy all the time but I still needed to feel better. I questioned whether I would ever feel like "ME" again. Also that I am somewhat irritable, and that the approach of winter weather has me concerned. She promised to Have me "tuned up" long before the bad weather sets in.
Hope to be able to report more in a week or so.
I appreciated the article by Dr. Kent on Medscape though I haven't finished it yet, seems to make sense so far. Anxiety has not been a big problem for me, thank goodness.
Hope there are others out there who will let us know their experiences with the WelLex combo.
Peace to us all.
Posted by Akman on September 21, 2003, at 23:11:03
In reply to Re: SSRIs and Beyond » lil' jimi, posted by oldhand on September 21, 2003, at 20:41:26
I've been taking Lexapro for about 3 weeks and recently began experiencing a pervasive, hallucinatory smell of stale cigars (and I don't smoke either!) Before I start looking elsewhere for an explanation I thought I would ask if anyone else has experienced any olfactory side effects from taking Lexapro.
Posted by PHV on September 22, 2003, at 0:07:41
In reply to Olfactory side effects?, posted by Akman on September 21, 2003, at 23:11:03
> I've been taking Lexapro for about 3 weeks and recently began experiencing a pervasive, hallucinatory smell of stale cigars (and I don't smoke either!) Before I start looking elsewhere for an explanation I thought I would ask if anyone else has experienced any olfactory side effects from taking Lexapro.
Have you ever been a cigar smoker - or around other cigar smokers? The reason I ask, is that I seem to smell cigarette smoke fairly frequently recently- when no one is smoking around me. I gave up cig smoking years ago - but seem to be especially sensitive to its scent. I sometimes smell it in my house - when no one is smoking. Interesting to see if they might be related. Thanks for posting and good luck. I look forward to hearing from you. Thanks.Patty
Posted by galkeepinon on September 22, 2003, at 1:21:05
In reply to escitalopram, posted by lil' jimi on September 21, 2003, at 20:18:54
Hey jim :-) took the weekend off so to speak~not feeling too well. I hope you're doing great!!!!
Anyway......in answer to your questions from my perspective/stance,>>>>>anybody's presciber mention even half of these? Actually I did some research about the med before I went on it, BUT I was sooooo depressed that I was willing to give another SSRI a shot Ha!!! Glad I did:-)
>>>>>anyone get any of this lowdown from their pharmacist? My pharmacist was very unhelpful, thank God my pdoc had started me on Lex and gave me the 2 month samples. She was way more knowledgeable on Lex than my pharmacist was!!When I went and got the script filled, the pharmacist basically said here ya go..
Boy, aren't you grateful we have a brain to think with and computers to do research on ;)
LOL
Have A Great Week jim:-)> hello everyone,
>
> here are some of the basics about lexapro we can get from online ... ... of particular interest, we have the list of side effects ...
>
> anybody's presciber mention even half of these?
> anyone get any of this lowdown from their pharmacist ?
>
> have a good week,
> ~ jim
>
> this is from http://www.medicinenet.com/escitalopram/article.htm
>
> GENERIC NAME: escitalopram
>
> BRAND NAME: Lexapro
> DRUG CLASS AND MECHANISM: Escitalopram is an oral drug that is used for treating depression. It is an antidepressant. It works by affecting neurotransmitters in the brain, the chemical messengers that nerves use to communicate with one another. Neurotransmitters are made and released by nerves and then travel to other nearby nerves where they attach to receptors on the nerves. Some neurotransmitters that are released do not bind to receptors and are taken up by the nerves that produced them. This is referred to as "reuptake."
>
> Many experts believe that an imbalance of neurotransmitters is the cause of depression. Escitalopram prevents the reuptake of one neurotransmitter, serotonin, by nerves, an action which results in more serotonin in the brain to attach to receptors. Chemically, escitalopram is very similar to citalopram. Both are in the class of drugs called selective serotonin reuptake inhibitors (SSRIs), a class that also includes fluoxetine (Prozac), paroxetine (Paxil) and sertraline (Zoloft).
>
> PRESCRIPTION: Yes
>
> GENERIC AVAILABLE: No
>
> PREPARATIONS: White to off-white, round tablets of 5, 10, and 20 mg.
>
> STORAGE: Escitalopram tablets should be stored at controlled room temperature, 59-86°F (15-30°C.)
>
> PRESCRIBED FOR: Escitalopram is used to treat depression. Drugs in the SSRI class also have been studied in persons with obsessive-compulsive disorders, general anxiety disorders, and panic disorders.
>
> DOSING: The usual starting dose of escitalopram is 10 mg once daily. Benefit may not be seen until treatment has been given for up to 4 weeks. Escitalopram can be taken with or without food. Older and younger persons require similar doses.
>
> DRUG INTERACTIONS: All SSRIs, including escitalopram, should not be taken together with any drugs of the MAO (mono-amine oxidase) inhibitor-class of antidepressants, for example, isocarboxazid (Marplan), phenelzine (Nardil), tranylcypromine (Parnate), and procarbazine (Matulane). Such combinations may lead to confusion, high blood pressure, high fevers, tremor or muscle rigidity, and increased activity. This same type of interaction also may occur with selegiline (Eldepryl), fenfluramine (Pondimin), and dexfenfluramine (Redux). Tryptophan can cause headaches, nausea, sweating, and dizziness when taken with any SSRI. At least 14 days should elapse after discontinuing escitalopram before starting a MAO inhibitor.
>
> PREGNANCY: The safety of escitalopram during pregnancy and lactation has not been established. Therefore, escitalopram should not be used during pregnancy unless, in the opinion of the physician, the expected benefits to the patient outweigh the possible hazards to the fetus.
>
> NURSING MOTHERS: Escitalopram is excreted in human milk. Escitalopram should not be given to nursing mothers unless, in the opinion of the physician, the expected benefits to the patient outweigh the possible hazards to the child.
>
> SIDE EFFECTS: The most commonly-noted side effects associated with escitalopram are agitation or restlessness, blurred vision, diarrhea, difficulty sleeping, drowsiness, dry mouth, fever, frequent urination, headache, indigestion, nausea, increased or decreased appetite, increased sweating, sexual difficulties (decreased sexual ability or desire, ejaculatory delay), taste alterations, tremor (shaking), weight changes. Although changes in sexual desire, sexual performance and sexual satisfaction often occur as a result of depression itself, they also may be a consequence of the drugs used to treat depression. In particular, about one in 11 men given escitalopram report difficulties experiencing ejaculation.
>
> Some patients may experience withdrawal reactions upon stopping SSRI therapy. Symptoms may include dizziness, tingling, tiredness, vivid dreams, irritability, or poor mood. In order to avoid these symptoms, the dose of SSRI can be slowly reduced instead of abruptly stopped.
>
Posted by galkeepinon on September 22, 2003, at 1:24:23
In reply to Olfactory side effects?, posted by Akman on September 21, 2003, at 23:11:03
Yep~weird. I experienced this on Topamax also. But with the Lexapro, I found that cigarettes taste/smell like stale cigars. Maybe it will get me to quit!! Hehehe
> I've been taking Lexapro for about 3 weeks and recently began experiencing a pervasive, hallucinatory smell of stale cigars (and I don't smoke either!) Before I start looking elsewhere for an explanation I thought I would ask if anyone else has experienced any olfactory side effects from taking Lexapro.
Posted by theo on September 22, 2003, at 8:12:48
In reply to Re: SSRIs and Beyond » lil' jimi, posted by oldhand on September 21, 2003, at 20:41:26
I'm on 150mg of the new Wellbutrin XL after being on 150mg of the SR for a month. I can tell the XL version is much smoother for me than the SR, and it is suppose to be. I was actually quite surprised because when Glaxo released Paxil CR and I made the switch to it from regular Paxil within two days I was having diarreah cramps about four hours after taking it. Went back to regular Paxil immediately and called my doc and he said it made no sense. I called a pharmacist at Glaxo and she asked me if I was "lactose intollerant" which I am not but she said there is HEAVY LACTOSE in the CR coating and fillers which was causing problems with a lot of people. Anyway that was back in my Paxil days but when I saw the reduced size of the Wellbutrin XL and the similiar shape to the CR, I was fearful of the new coating but it's fine.
Anyway the main reason for the post is my pdoc suggested adding 5mg of Lex to my 150mg of Wellbutrin XL and I started low with 2.5mg yesterday and in a few days will go to 5mg. A few months ago I took Lex by itself for about six weeks but my general doc threw me a bag of samples and said "all you do is just start with 10mg." Well that didn't work so well and I quit because of the sides, so I'm slowly easing into the Lex this time. So far so good but keep me posted on your "WellPro Combo" progress and I will do the same.
Thanks,
Theo aka Ted
Posted by Kacy on September 22, 2003, at 9:13:15
In reply to Re: Olfactory side effects? » Akman, posted by galkeepinon on September 22, 2003, at 1:24:23
Maybe you have a more sensitive nose on the drug. Could you be smelling a lingering odor on some clothes in a closet that you wore somewhere around smokers, or from upholstery that had been subject to the smoke, or to the odor on walls in a room where people have smoked?
Posted by galkeepinon on September 22, 2003, at 15:23:55
In reply to Re: Olfactory side effects?, posted by Kacy on September 22, 2003, at 9:13:15
Hi Kacy, I laughed when I saw this because I was laughing at myself. I spray, spray, and spray, and then some LOL to get rid of this smokey stench!
I have, mmmmm,let's see, Lysol, a nice scent of Glade air freshner, and a Glade 'plug-in' in my wall to help with the smell. I wash my clothes and plop in 2 Bounce sheets too. All these things help me a lot with that nasty 'stench', just think what I'm doing to my lungs. YIKES.
I only smoke when I'm on the computer at night in my room, otherwise I smoke outside. But I got a HUGE headache today, so I need to lay off the cancer sticks for a while!!> Maybe you have a more sensitive nose on the drug. Could you be smelling a lingering odor on some clothes in a closet that you wore somewhere around smokers, or from upholstery that had been subject to the smoke, or to the odor on walls in a room where people have smoked?
>
>
Posted by galkeepinon on September 22, 2003, at 16:02:17
In reply to re: Gal, et al, posted by lil' jimi on September 20, 2003, at 2:28:02
Posted by lil' jimi on September 22, 2003, at 16:33:14
In reply to re: Gal~~~I'm drinking a ton of water jim:-):-) (nm) » lil' jimi, posted by galkeepinon on September 22, 2003, at 16:02:17
Posted by galkeepinon on September 22, 2003, at 18:07:52
In reply to Excellent !! How's it taste ? :-):-) 8^) (nm) » galkeepinon, posted by lil' jimi on September 22, 2003, at 16:33:14
Hey jim:-)
I just think that drinking a lot of water is essential with all these meds going in our systems!!!
It feels so refreshing to know that I can control somewhat the flushing of my kidneys.
Here's to 8 cups of water a day~~for EVERYONE:-)
Go Lexaproooooooooooooooo:-)
Posted by lil' jimi on September 22, 2003, at 19:20:31
In reply to Refreshing ahhhhhhhhh 2 more to go............. » lil' jimi, posted by galkeepinon on September 22, 2003, at 18:07:52
....
.... and _you_ have reminded _me_ to drink some more water ... ... !!so .....
Here's to Lexapro!
Hip! Hip!
Posted by galkeepinon on September 22, 2003, at 19:39:04
In reply to Re: Refreshing ahhhhhhhhh .... more to go....... » galkeepinon, posted by lil' jimi on September 22, 2003, at 19:20:31
> .... and _you_ have reminded _me_ to drink some more water ... ... !!
>
> so .....
>
> Here's to Lexapro!
> Hip! Hip!...................
...............
HOORAYYYYYYYYYY!!! Ha lol :-)
Posted by BLKVETTES on September 22, 2003, at 19:42:36
In reply to Excellent !! How's it taste ? :-):-) 8^) (nm) » galkeepinon, posted by lil' jimi on September 22, 2003, at 16:33:14
ALL WATER POSTS SHOULD BE REDIRECTED TO HA! I LOVE MY WATER HA! PHYCHO BABBLE LINK!!!!!!!
Posted by lil' jimi on September 22, 2003, at 20:35:56
In reply to Re: Excellent !! How's it taste ? :-):-) 8^), posted by BLKVETTES on September 22, 2003, at 19:42:36
Posted by lil' jimi on September 22, 2003, at 20:37:49
In reply to Re: Refreshing ahhhhhhhhh .... more to go....... » lil' jimi, posted by galkeepinon on September 22, 2003, at 19:39:04
Posted by galkeepinon on September 22, 2003, at 20:54:35
In reply to Hip ! Hip !! (nm) » galkeepinon, posted by lil' jimi on September 22, 2003, at 20:37:49
Posted by KimberlyDi on September 23, 2003, at 15:17:46
In reply to Re: Olfactory side effects? » Akman, posted by PHV on September 22, 2003, at 0:07:41
SSRI's sweating through your pores?
Hey, what's odd to me is that sometimes I smell the "stale cigarette" odor. But what's worse, my husband has accused me of either starting smoking or having an affair with someone who does. I don't and I haven't!!! But it's been a mystery to me!
KDi in Texas
> > I've been taking Lexapro for about 3 weeks and recently began experiencing a pervasive, hallucinatory smell of stale cigars (and I don't smoke either!) Before I start looking elsewhere for an explanation I thought I would ask if anyone else has experienced any olfactory side effects from taking Lexapro.
>
>
> Have you ever been a cigar smoker - or around other cigar smokers? The reason I ask, is that I seem to smell cigarette smoke fairly frequently recently- when no one is smoking around me. I gave up cig smoking years ago - but seem to be especially sensitive to its scent. I sometimes smell it in my house - when no one is smoking. Interesting to see if they might be related. Thanks for posting and good luck. I look forward to hearing from you. Thanks.
>
> Patty
>
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