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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 5 of 5. This is the beginning of the thread.
Posted by Ame Sans Vie on July 26, 2003, at 11:49:26
Does anyone know if we can ever expect this to hit the market here in the States? It sounds great... benzodiazepine partial agonist, *and* 5HT/NE release. So anyone have any good news for me? :-)
Posted by djmmm on July 26, 2003, at 15:50:06
In reply to Deracyn (adinazolam), posted by Ame Sans Vie on July 26, 2003, at 11:49:26
> Does anyone know if we can ever expect this to hit the market here in the States? It sounds great... benzodiazepine partial agonist, *and* 5HT/NE release. So anyone have any good news for me? :-)
I suspect it isn't very different than Xanax, another triazolobenzodiazepine, as far as anti-anxiety/antidepressant effects are concerned
Posted by SLS on July 26, 2003, at 15:56:06
In reply to Re: Deracyn (adinazolam), posted by djmmm on July 26, 2003, at 15:50:06
> > Does anyone know if we can ever expect this to hit the market here in the States? It sounds great... benzodiazepine partial agonist, *and* 5HT/NE release. So anyone have any good news for me? :-)
>
> I suspect it isn't very different than Xanax, another triazolobenzodiazepine, as far as anti-anxiety/antidepressant effects are concerned
Adinazolam does display a more robust antidepressant effect than does alprazolam (Xanax). I tried it in the mid 1980s. It was virtually devoid of side effects. Unfortunately, it did nothing for me. However, my doctor at the time was astounded to see so many of his patients respond to it. He had previously thought that it would be useless. It is too bad it is not available in the US. I doubt it will be.
- Scott
Posted by wild_caver on January 4, 2006, at 16:07:45
In reply to Re: Deracyn (adinazolam), posted by SLS on July 26, 2003, at 15:56:06
I have been reading about adinazolam and I am hopeful that it will become available in the USA. I have anxiety/panic attacks (with family history of same) and winter depression for which I take escitalopram. For anxiety, my primary care physician prescribes diazepam 5mg bid prn however I perceive both antidepressant and anxiolytic effects with alprazolam. I have read studies confirming the antidepressant effects associated with triazolobenzodiazepines. Along with excercise, avoidance of caffeine, and management of diet, I would be very receptive to therapy with adinazolam. Over the past 20 years, I have been treated too aggressively (in my opinion) for bipolar disorder (although I have not experienced a hypomanic episode in 15 years) with mood stabilizers, antipsychotics, hypnotics, and antidepressants simultaneously resulting in weight gain (160 normally up to 187 lbs) and feeling like a zombie, which affected my work performance (research and writing scientific papers), limited my ability to excercise, and decreased my overall quality of life without bringing significant relief of my symptoms. I could not maintain compliance (or afford it) while gulping a handful of pills every day. A single therapeutic agent like adinazolam would be a godsend.
Posted by SLS on January 8, 2006, at 19:48:45
In reply to Re: Deracyn (adinazolam) » SLS, posted by wild_caver on January 4, 2006, at 16:07:45
Adinazolam is a very clean drug. When I was taking it, I experienced no physical, sedative, or cognitive side effects. It does seem to display robust antidepressant effects according to the doctor who had treated me with it, despite my not responding to it. You might indeed be able to glean an adequate antidepressant and anxiolytic effects from the one drug.
I doubt adinazolam will be introduced to the US. There was some interest in it in the mid 1980s, but there has been little or no work done on it since. Perhaps the patent has run out.
- Scott
> I have been reading about adinazolam and I am hopeful that it will become available in the USA. I have anxiety/panic attacks (with family history of same) and winter depression for which I take escitalopram. For anxiety, my primary care physician prescribes diazepam 5mg bid prn however I perceive both antidepressant and anxiolytic effects with alprazolam. I have read studies confirming the antidepressant effects associated with triazolobenzodiazepines. Along with excercise, avoidance of caffeine, and management of diet, I would be very receptive to therapy with adinazolam. Over the past 20 years, I have been treated too aggressively (in my opinion) for bipolar disorder (although I have not experienced a hypomanic episode in 15 years) with mood stabilizers, antipsychotics, hypnotics, and antidepressants simultaneously resulting in weight gain (160 normally up to 187 lbs) and feeling like a zombie, which affected my work performance (research and writing scientific papers), limited my ability to excercise, and decreased my overall quality of life without bringing significant relief of my symptoms. I could not maintain compliance (or afford it) while gulping a handful of pills every day. A single therapeutic agent like adinazolam would be a godsend.
This is the end of the thread.
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