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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 8 of 8. This is the beginning of the thread.
Posted by ace on June 22, 2003, at 22:43:26
Hey critters!,
In my quest for OCD destruction I thought about these 2 instead of maybe adding Zyprexa - are they safe with Nardil? Either on or both?
Thanks folks,
Ace.
Posted by Caleb462 on June 22, 2003, at 23:05:53
In reply to Reboxetine/Buspar OK with Nardil?, posted by ace on June 22, 2003, at 22:43:26
> Hey critters!,
>
> In my quest for OCD destruction I thought about these 2 instead of maybe adding Zyprexa - are they safe with Nardil? Either on or both?
>
> Thanks folks,
>
> Ace.Buspar should be fine, I think.
Reboxetine is probably listed as a NO, however... I would think it would be ok to add a low dose under a doc's supervision, as long as your doc is cool with it.
Posted by ACE on June 23, 2003, at 1:10:49
In reply to Re: Reboxetine/Buspar OK with Nardil?, posted by Caleb462 on June 22, 2003, at 23:05:53
> Buspar should be fine, I think.
>
> Reboxetine is probably listed as a NO, however... I would think it would be ok to add a low dose under a doc's supervision, as long as your doc is cool with it.As far as I've read Buspar could have deleterious effects on BP with Nardil- what do you think?
Reboxetine is a noradrenalin agonist- how would this cause 5HT syndrome with Nardil?
Give us some advice Caleb and others!
Ace...
Posted by Caleb462 on June 23, 2003, at 1:16:38
In reply to Buspar + Nardil- BP risk? with Reboxetine?, posted by ACE on June 23, 2003, at 1:10:49
>
> > Buspar should be fine, I think.
> >
> > Reboxetine is probably listed as a NO, however... I would think it would be ok to add a low dose under a doc's supervision, as long as your doc is cool with it.
>
> As far as I've read Buspar could have deleterious effects on BP with Nardil- what do you think?Admittedly, I didn't do any reading on it. So yeah, that does seem to be the case. Again though, it is probably something that could be OK as long as dosage is watched closely and BP is monitered.
> Reboxetine is a noradrenalin agonist- how would this cause 5HT syndrome with Nardil?
>It wouldn't cause 5HT syndrome... but it COULD cause a hypertensive crisis.
Posted by ACE on June 23, 2003, at 1:24:11
In reply to Re: Buspar + Nardil- BP risk? with Reboxetine?, posted by Caleb462 on June 23, 2003, at 1:16:38
Posted by ace on June 23, 2003, at 2:53:25
In reply to Thanks Caleb- I'll link you to an article soon... (nm), posted by ACE on June 23, 2003, at 1:24:11
Let me know what you think
www.reboxetine.com/Also, a old post here in 1999 'Re: MAOI/Reboxetine Combo For "Cheese Effect"- just wack it in the search
Thanks man,
Ace.
Posted by SLS on June 23, 2003, at 6:10:43
In reply to Re: Reboxetine/Buspar OK with Nardil?, posted by Caleb462 on June 22, 2003, at 23:05:53
Hi.
> Buspar should be fine, I think.Possibly not. I have played with a bunch of combinations involving MAOIs, so I am not very timid about using them. It is not buspirone that concerns me, but its principle metabolite, 1-(2-pyrimidinyl)-piperazine (1-PP). It is a potent NE alpha-2 receptor antagonist. As such, it works a lot like Remeron (mirtazapine), and yields an increase of norepinephrine in the synaptic cleft via increased synthesis and release.
> Reboxetine is probably listed as a NO, however... I would think it would be ok to add a low dose under a doc's supervision, as long as your doc is cool with it.
Theoretically, if one considers reboxetine to be a selective NE reuptake inhibitor without any other pharmacological properties, it should be safe to combine it with MAOIs. However, one cannot assume that reboxetine is without any other properties that would interact adversely with an MAOI. I have successfully combined Nardil with desipramine, another "selective" antidepressant that is known to have many other properties.
- Scott
Posted by Questionmark on June 24, 2003, at 3:29:20
In reply to Re: Reboxetine/Buspar OK with Nardil?, posted by SLS on June 23, 2003, at 6:10:43
i've read somewhere that reboxetine can actually be helpful in *preventing* hypertensive crises. How this would be the case i have no idea. But yeah.
This is the end of the thread.
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