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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 6 of 6. This is the beginning of the thread.
Posted by SLS on May 4, 2003, at 10:01:23
I recently added Provigil to my cocktail. It is the second time I've tried it, but the first in combination with antidepressants. Both times, I received a significant mood-lift within an hour of the first dose. After that, nothing. In fact, I think it might be making me feel foggy-headed and a little worse. It's hard to tell. Does this sound familiar to anyone?
My current doctor thinks that a combination of Lamictal + Parnate + Provigil might work for me. Has anyone combined Lamictal + Provigil?
Thanks for any input.
- Scott
Posted by Emme on May 4, 2003, at 11:51:06
In reply to Provigil, posted by SLS on May 4, 2003, at 10:01:23
Yes, I have taken provigil with lamictal. I can't really tolerate the provigil for more than a few days at a time, but I have found it helpful. It seemed to flip the switch so to speak, and stop the decline into horrible depression. I don't recall feeling foggy headed on it. But it was stimulating enough that it was hard to settle down. I haven't taken it with an antidepressant.
Emme
> I recently added Provigil to my cocktail. It is the second time I've tried it, but the first in combination with antidepressants. Both times, I received a significant mood-lift within an hour of the first dose. After that, nothing. In fact, I think it might be making me feel foggy-headed and a little worse. It's hard to tell. Does this sound familiar to anyone?
>
> My current doctor thinks that a combination of Lamictal + Parnate + Provigil might work for me. Has anyone combined Lamictal + Provigil?
>
> Thanks for any input.
>
>
> - Scott
Posted by jemma on May 4, 2003, at 19:32:12
In reply to Re: Provigil » SLS, posted by Emme on May 4, 2003, at 11:51:06
I've taken modafinil for several months now, and it keeps me awake and relatively cheerful. I tried some lamictal with it, and immediately my mood declined. Modafinil raises glutamate; lamictal lowers glutamate and raised gaba. I think my brain needs the boost from glutamate, and the lamictal was cancelling it out. I'm happier now on modafinil and selegiline.
- jemma
Posted by JackT on May 5, 2003, at 11:22:46
In reply to Re: Provigil, posted by jemma on May 4, 2003, at 19:32:12
Jemma,
I have been interested in selegiline for some time, but my pdoc will not prescribe it for GAD. What symptoms are being helped by it and can you offer any advice to get my pdoc to try it?
Nothing but the benzos work for my anxiety and I don't like their side effects. That leaves me always looking for "a new drug". A side effect from my anxiety is always feeling tired and down (not fully depressed though). I am also interested in hearing more about your modafinil experience. I have tried ritalin with little success and my pdoc is also unwilling to try modafinil.
Posted by jemma on May 5, 2003, at 19:23:43
In reply to Re: Provigil » jemma, posted by JackT on May 5, 2003, at 11:22:46
Jack,
Modafinil is terrific for treating my low-energy, sleeping-too-much, no-motivation form of depression. It doesn't really treat anxiety - in fact, it can cause it. It's not a stimulant, but it behaves like one.
Good luck finding something that works.
- jemma
Posted by jemma on May 5, 2003, at 19:27:44
In reply to Re: Provigil » jemma, posted by JackT on May 5, 2003, at 11:22:46
Oops, you asked about selegiline, not modafinil. But my answer would be pretty much the same. Low-dose selegiline acts selectively to increase dopamine levels. It's activating rather than calming, and therefore I would think not very useful for anxiety.
- jemma
This is the end of the thread.
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