Psycho-Babble Medication Thread 218774

Shown: posts 1 to 7 of 7. This is the beginning of the thread.

 

TD and SSRI's

Posted by disney4 on April 12, 2003, at 11:28:47

I have read a few reports of TD cases evolving when the only med involved was an SSRI. I am considering going back on Serzone, but this scared me more than the liver scare. Does anyone have any knowledge of this?

 

Re: TD and SSRI's

Posted by den2 on April 12, 2003, at 11:41:51

In reply to TD and SSRI's, posted by disney4 on April 12, 2003, at 11:28:47

I have bad TD from long term paxil use. It's probably because there is movement disorders in my family(ex. parkinsons, tourrett's syndrome) I take remeron and it has cured the TD I had from paxil. Also it is a very good antidepressant with no side effects.

 

Re: TD and SSRI's

Posted by linkadge on April 12, 2003, at 12:15:27

In reply to TD and SSRI's, posted by disney4 on April 12, 2003, at 11:28:47

From the pharmokinetics serzone would have a smaller probability of causing TD. It inhances norepinephrine transmission which helps to preserve dopamine. And if you're really scared
try Remeron. No liver problem and it can actually improve the symptoms of movement disorders.


Good Luck

Linkadge

 

linkadge, Re: TD and SSRI's

Posted by McPac on April 12, 2003, at 22:46:29

In reply to Re: TD and SSRI's, posted by linkadge on April 12, 2003, at 12:15:27

link, Which causes TD problems for some folks, is it the drugs that LOWER dopamine levels OR is it the drugs that RAISE dopamine levels? thanks!

 

Re: linkadge, Re: TD and SSRI's

Posted by linkadge on April 13, 2003, at 10:10:04

In reply to linkadge, Re: TD and SSRI's, posted by McPac on April 12, 2003, at 22:46:29

Generally it is seen as a result of drugs that lower dopamine. The antispsychotis lower dopamine, and the SSRI's *can* lower dopamine indirectly by raising serotonin.

The SSRI risk of TD is extremely low. And if the symptoms occur they are progressive not spontainious. Unlike some sntispyhotics, SSRI TD can be ameliorated simply by reduction of dose.


And like I said there have been numerious studies suggesting Remeron is the drug to use in movement disorders. It has been shown to reduce some disorders significantly.

There are ways to reduce the relative risk of TD with SSRIs. Fish oil and Vitamin E are being studied for this.

Linkadge

 

link, Re: linkadge, Re: TD and SSRI's

Posted by McPac on April 13, 2003, at 20:32:49

In reply to Re: linkadge, Re: TD and SSRI's, posted by linkadge on April 13, 2003, at 10:10:04

One other question, please, what dosage of Remeron is used to reduce the movement disorder? Does it just partially help the movement problem or does it seem to work very well for that? Thanks!

 

Re: link, Re: linkadge, Re: TD and SSRI's

Posted by linkadge on April 14, 2003, at 9:14:41

In reply to link, Re: linkadge, Re: TD and SSRI's, posted by McPac on April 13, 2003, at 20:32:49

The standard dose of 15 mg, has been shown to improve depression and reduce movement disorders.

I am not entirely shure to what degree it helps, but one story of the improvement involved a geriatric lady who had given up card playing because tremors made it too difficult and embarrasing. After treatment with Rem, the lady
was not only more confident, but was able to
play the game again, with significantly reduced tremors.


It is a good drug. Essentially it has only two side effects which are increased apetite and sedation. The sedation is said only to be temporary.

In my opinion it can be a good drug for augmentation.


The last thing to note is that TD is very rare with SSRI's. And, that the risk is unequal between the SSRI's. Zoloft has minimal risk.


Linkadge


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