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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 4 of 4. This is the beginning of the thread.
Posted by HelenInCalif on April 5, 2003, at 23:50:26
Last week I had started generic Dexedrine and found it wasn't working well at all (as compared to months of good results with Dex spansules (5mg 2x day)). I'd been thinking that somehow I was reacting differently to generic vs. name brand dexedrine. But in thinking about it- perhaps one other factor is causing the difference.
10 days ago I had started taking Ambien (recent insomnia starting mid-March due to work stress. Melatonin wasn't working and OTC = groggy the next day). My old Dex prescription had run out a bit before that, so I'd never had both at the same time. Is there some chance that Ambien interferes with dexedrine? I take Ambien at 11pm (2.5 to 5 mg) and the d-amphetamine at 9-10am and 1-2pm (5mg each).
Posted by Caleb462 on April 6, 2003, at 1:40:21
In reply to Could Ambien interfere with Dexedrine for ADD?, posted by HelenInCalif on April 5, 2003, at 23:50:26
> Last week I had started generic Dexedrine and found it wasn't working well at all (as compared to months of good results with Dex spansules (5mg 2x day)). I'd been thinking that somehow I was reacting differently to generic vs. name brand dexedrine. But in thinking about it- perhaps one other factor is causing the difference.
>
> 10 days ago I had started taking Ambien (recent insomnia starting mid-March due to work stress. Melatonin wasn't working and OTC = groggy the next day). My old Dex prescription had run out a bit before that, so I'd never had both at the same time. Is there some chance that Ambien interferes with dexedrine? I take Ambien at 11pm (2.5 to 5 mg) and the d-amphetamine at 9-10am and 1-2pm (5mg each).
Not likely, particularly if the dose is only 2.5 to 5 mg. Ambien is pretty much out of your system after a full night's sleep (8 hours). Perhaps you just need a larger dose of dex?
Posted by HelenInCalif on April 6, 2003, at 4:43:04
In reply to Re: Could Ambien interfere with Dexedrine for ADD?, posted by Caleb462 on April 6, 2003, at 1:40:21
Other than the switch to the generic brand, taking Ambien is the only major change that correlates with my ADD being back in full force last week*. I know correlation isn't causation and all that, but I should ask here just in case. I really need to figure out why I couldn't focus last week even with doubling my dose or with trying Ritalin again.
As mentioned in my original thread (on 4/3), with the generic I started at 5mg 2x day. When I felt no effect I then doubled it to 10mg 2x day: still nothing. ADD-wise it was still as if I was taking a placebo. For months I'd successfully used (name brand) dexedrine without developing any tolerance, and that's why I'd asked if there could be a difference between Dex spansules and the generic (Barr) d-amph. On Friday I went back to Ritalin (had some left over from a while ago). But even the Ritalin didn't work fully, which is why I'm researching if the Ambien could interfere.
(* And my stress levels at work are higher, but that is an effect of the ADD being back, not a cause, I think.)
Posted by Caleb462 on April 7, 2003, at 3:59:01
In reply to Re: Could Ambien interfere with Dexedrine for ADD?, posted by HelenInCalif on April 6, 2003, at 4:43:04
> Other than the switch to the generic brand, taking Ambien is the only major change that correlates with my ADD being back in full force last week*. I know correlation isn't causation and all that, but I should ask here just in case. I really need to figure out why I couldn't focus last week even with doubling my dose or with trying Ritalin again.
>
> As mentioned in my original thread (on 4/3), with the generic I started at 5mg 2x day. When I felt no effect I then doubled it to 10mg 2x day: still nothing. ADD-wise it was still as if I was taking a placebo. For months I'd successfully used (name brand) dexedrine without developing any tolerance, and that's why I'd asked if there could be a difference between Dex spansules and the generic (Barr) d-amph. On Friday I went back to Ritalin (had some left over from a while ago). But even the Ritalin didn't work fully, which is why I'm researching if the Ambien could interfere.
>
> (* And my stress levels at work are higher, but that is an effect of the ADD being back, not a cause, I think.)
Well... I dunno... but I really doubt Ambien has anything to do with it. Granted, it's possible.. but not likely.Brand names and generics do have some differences sometimes in the amount of the drug that appears in the bloodstream at any given time, even if the dosages are the same. For most people, there is no difference, but for an unlucky few, there is.
This is the end of the thread.
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