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Dr. Bob is Robert Hsiung, MD,
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Posted by glenn on October 21, 2002, at 14:44:19
Time response for antidepressant action.
Just thought it might be interesting to share my little analysis of treatment responses from the book - Living with Prozac and other Ssris.
Basically people responded in the following time scales:
0-1 weeks - 6
1-2 weeks - 2
2-3 weeks - 5
3 weeks+ - 17
There were about 10 instant responses and 20 gradual ones
I wonder if people are responding due to different effects of the ads. Those for example who respond very quickly, sometimes in a matter of hours may truly be suffering from a serotonin deficit, a somewhat discredited idea nowadays. Likewise those taking longer may be benefiting from downstream effects such as downregulation and hippocampal nerve regrowth.Maybe all the theories have validity, or maybe it just depends how long you have been depressed for.
Just more musing.
Glenn
Posted by Jackster on October 22, 2002, at 0:17:55
In reply to Times of Response to ads, posted by glenn on October 21, 2002, at 14:44:19
Hi Glenn
Interesting thought - I'd been wondering about the so called 'instant responses'. From what I've read it seems that the first effects we get from an AD are the side effects. Some of the SSRIs are quite activating (eg Prozac, Zoloft)- kind of like having several coffees at once. So the response time would depend on why you are taking the AD. If you suffer from panic disorder (like myself) it would take a few weeks before the activating effect calmed down and you received the real benefit of the AD. (Less anxious etc). Hence response time could be up to 6-8 weeks. If you were taking the medication because you were depressed in a very lack of energy, no motivation way - you could take the activating side effect of the AD to be the drug kicking in, and would consider your response to be only 1-2 weeks.
Just a thought.
Jackie
> Time response for antidepressant action.
>
> Just thought it might be interesting to share my little analysis of treatment responses from the book - Living with Prozac and other Ssris.
>
> Basically people responded in the following time scales:
>
> 0-1 weeks - 6
>
> 1-2 weeks - 2
>
> 2-3 weeks - 5
>
> 3 weeks+ - 17
>
> There were about 10 instant responses and 20 gradual ones
>
>
> I wonder if people are responding due to different effects of the ads. Those for example who respond very quickly, sometimes in a matter of hours may truly be suffering from a serotonin deficit, a somewhat discredited idea nowadays. Likewise those taking longer may be benefiting from downstream effects such as downregulation and hippocampal nerve regrowth.
>
> Maybe all the theories have validity, or maybe it just depends how long you have been depressed for.
>
> Just more musing.
>
> Glenn
Posted by Denise528 on October 22, 2002, at 7:49:28
In reply to Re: Times of Response to ads, posted by Jackster on October 22, 2002, at 0:17:55
Hi,
I Just wanted to say that ADs worked very quickly for me, in a matter of days. I suffered mainly from depression (lack of motivation, tiredness etc) rather than anxiety and yes I did find the drugs activating but in a very positive way, they relaxed me, yet gave me more motivation and energy and definately lifted my mood without a shadow of a doubt(all within days). This time round, they have still been activating but in a horrible, destructive kind of way and they definately haven't lifted my depression. So I don't agree with your theory that it is the activation itself that is interpretation of an instant response. At least I think that is what you're saying, correct me if I'm wrong.Denise
Denise
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