Psycho-Babble Medication Thread 108774

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Long-term efficacy duration of tri's

Posted by Squiggles on June 5, 2002, at 11:47:28

Hi everyone,

This is not for my case (i take the miracle
drug lithium - just terrified about kidneys
all the time :-);

it's about tricyclics: is it possible that
tricylic ADs can "poop" out or lose their
strength when taken over a long period of
time - say 15 yrs? ( i suppose so many other
intervening factors could be involved), but in
itself, is this a possibity in your experience?

Thanks

Squiggles

 

Re: Long-term efficacy duration of tri's

Posted by Elizabeth on June 7, 2002, at 2:05:56

In reply to Long-term efficacy duration of tri's, posted by Squiggles on June 5, 2002, at 11:47:28

Poop-out is a really variable thing; some people can take Drug X for many years and it still works, for others it poops out after a year or two. But I have heard a couple reports of tricyclic poop-out. I don't know how common it is compared with SSRI poop-out, because tricyclics are so rarely used these days.

Re lithium: are you getting your serum Li+ and electrolyte levels checked regularly? If so, I'd say that you're fine: impaired renal functioning should be reversible by going off the lithium. (Of course, it would mean you'd have to find a different medication.)

 

Re: Long-term efficacy duration of tri's

Posted by Squiggles on June 7, 2002, at 6:24:59

In reply to Re: Long-term efficacy duration of tri's, posted by Elizabeth on June 7, 2002, at 2:05:56

Thank you Elizabeth;
and for the lithium advice - actually i asked
my dr. if he could check me for kidneys - i
keep worrying about my kidneys - probably get
a creatine test.


tx for your attention

Squiggles


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