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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 9 of 9. This is the beginning of the thread.
Posted by jonh kimble on May 20, 2002, at 19:02:53
well, here i am after 5 years of pretty darn bad dysthymia and sp (and a life time of mild dysthymia and sp) in that time there has been 10 books read, 20 psychologist visits, and a dozen ad trials, including luvox, paxil, wellbutrin, parnate, nardil, selegeline, dexedrine, anafranil, ritalin, adrafinil, effexor... and all for at least 4 weeks. and its not because too many side effects (although they were there) no med has ever helped for more than a couple days.
my question is: has anybody found help for their dysthymia and sp? any info would be great, but especially info about people who have been treatment resistent. i am somewhat hopeful about amisulpride and mirapex, but, i have also been hopeful about a lot of things that didnt turn out...
id love to here any info. please, ANYTHING.
jon
Posted by janejj on May 20, 2002, at 19:18:52
In reply to any hope left for a dysthymic?, posted by jonh kimble on May 20, 2002, at 19:02:53
Hi John,
I have also been diagnosed as dysthymic. I felt really sad when the doctor told me that, wish he hadn't in way, because all that self fulfilling prophecy stuff.
Anyway I am currently taking 50mg of Prozac as well as Trazodone at night and B vitamin complex. I am pretty happy right now, life seems to working out OK. I sometimes wonder if the situation that you find yourself in is a major cause of Dysthmia. Are you happy with the things you have done with your life ? You have to remember that you must always make decisions which will lead you to a happier place. Even if it means leaving all the mundane things that make life crap and doing something that you really, really want to do. I know its hard when you have dysthymia to make decisions etc, just a thought.
Have you tried Prozac ? I didn't see it on your list.
Posted by JonW on May 20, 2002, at 20:37:38
In reply to any hope left for a dysthymic?, posted by jonh kimble on May 20, 2002, at 19:02:53
Hi Jon,
I have problems somewhat similar to yours and I'll let you and the world for that matter know the second I find something that works! :) I know it sucks... Anyway, what are your symptoms exactly? Someone here might have an insight given more specific info. Have you ever tried prozac + zyprexa. There were a couple of recent studies showing this combo effective for treatment resistent depression. It apparently causes a marked increase in serotonin, norepinephrine, and dopamine instead of just serotonin. Who knows if that has anything to do with it, but it might be worth a try right?
Good luck,
Jon> well, here i am after 5 years of pretty darn bad dysthymia and sp (and a life time of mild dysthymia and sp) in that time there has been 10 books read, 20 psychologist visits, and a dozen ad trials, including luvox, paxil, wellbutrin, parnate, nardil, selegeline, dexedrine, anafranil, ritalin, adrafinil, effexor... and all for at least 4 weeks. and its not because too many side effects (although they were there) no med has ever helped for more than a couple days.
>
> my question is: has anybody found help for their dysthymia and sp? any info would be great, but especially info about people who have been treatment resistent. i am somewhat hopeful about amisulpride and mirapex, but, i have also been hopeful about a lot of things that didnt turn out...
>
> id love to here any info. please, ANYTHING.
>
> jon
Posted by turalizz on May 21, 2002, at 0:34:59
In reply to any hope left for a dysthymic?, posted by jonh kimble on May 20, 2002, at 19:02:53
> well, here i am after 5 years of pretty darn bad dysthymia and sp (and a life time of mild dysthymia and sp) in that time there has been 10 books read, 20 psychologist visits, and a dozen ad trials, including luvox, paxil, wellbutrin, parnate, nardil, selegeline, dexedrine, anafranil, ritalin, adrafinil, effexor... and all for at least 4 weeks. and its not because too many side effects (although they were there) no med has ever helped for more than a couple days.
>
> my question is: has anybody found help for their dysthymia and sp? any info would be great, but especially info about people who have been treatment resistent. i am somewhat hopeful about amisulpride and mirapex, but, i have also been hopeful about a lot of things that didnt turn out...
>
> id love to here any info. please, ANYTHING.
>
> jonMoclobemide has been the answer for me.
cem
Posted by jonh kimble on May 22, 2002, at 17:32:12
In reply to any hope left for a dysthymic?, posted by jonh kimble on May 20, 2002, at 19:02:53
Thank you all for your posts. yes, i am beggining to see that doing some of the hardest things in life like achieving goals is one of the best ways to get out of the rut. that may sound obvious, but it can be hard to have hope and motivation when you're dysthymic.
as far as meds go, i have tried ALOT of serotonin drugs with absolutely no response. this makes me hesitate to try prozac or mocolonmide (i know wrong spelling). and jon, where did you see the studies on prozac plus zyprexa? interesting that this combo has such a great effect on all three major monoamines. i am going to see a hospital based pschiatrist soon. any chance they would prescribe amisulpride? (i live in canada, its not available here) what info should i give him to make him more comfortable with the idea? all your posts are helpful. thanks
Oh ya, i saw my family doc yesterday and i asked to try klonopin for the social anxiety, and he said since i didnt have a problem with hallucinating that it wouldnt help. What the hell? maybe next time i come in with the flu he'll prescribe me amisulpride. jj
jon
Posted by Zo on May 24, 2002, at 17:29:37
In reply to any hope left for a dysthymic?, posted by jonh kimble on May 20, 2002, at 19:02:53
I think it terribly handicaps one's case to seek or expect to find relief via one single drug.
Certainly not if one has tried a number, and no one med has worked. My slogan, Don't switch, augment!
Zo
Posted by JonW on May 24, 2002, at 19:18:37
In reply to Re: any hope left for a dysthymic?, posted by jonh kimble on May 22, 2002, at 17:32:12
> as far as meds go, i have tried ALOT of serotonin drugs with absolutely no response. this makes me hesitate to try prozac or mocolonmide (i know >wrong spelling). and jon, where did you see the studies on prozac plus zyprexa? interesting that this combo has such a great effect on all three major >monoamines. i am going to see a hospital based pschiatrist soon. any chance they would prescribe amisulpride? (i live in canada, its not available >here) what info should i give him to make him more comfortable with the idea? all your posts are helpful. thanks
Hi Jon,
I've come across a couple of medline abstracts that talk about prozac + zyprexa for treatment resistant depression. Here, let me past them below:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11874227&dopt=Abstract
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11136647&dopt=Abstract
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10942849&dopt=AbstractWhen you say you are going to see a hospital doc I'm not sure what you mean. If this is a doctor involved with research at a university hospital, he should at least be open to discussing the use of drugs like amisulpride. I would send him a fax before your appointment to tell him your thoughts and include an abstract that supports the use of amisulpride for dysthymia. Here's such an abstract:
> Oh ya, i saw my family doc yesterday and i asked to try klonopin for the social anxiety, and he said since i didnt have a problem with hallucinating >that it wouldnt help. What the hell? maybe next time i come in with the flu he'll prescribe me amisulpride. jj
LOL! This made me laugh at first... but as someone with severe social anxiety it burns my buttocks! :) Even if you didn't know that Klonopin is often used to treat social phobia, it's nothing new that these drugs are anti-anxiety agents! Don't walk, but run from this doctor! Thank god you're going to see a psychiatrist soon.
Good Luck,
Jon
Posted by JohnX2 on May 25, 2002, at 1:27:08
In reply to any hope left for a dysthymic?, posted by jonh kimble on May 20, 2002, at 19:02:53
> well, here i am after 5 years of pretty darn bad dysthymia and sp (and a life time of mild dysthymia and sp) in that time there has been 10 books read, 20 psychologist visits, and a dozen ad trials, including luvox, paxil, wellbutrin, parnate, nardil, selegeline, dexedrine, anafranil, ritalin, adrafinil, effexor... and all for at least 4 weeks. and its not because too many side effects (although they were there) no med has ever helped for more than a couple days.
>
> my question is: has anybody found help for their dysthymia and sp? any info would be great, but especially info about people who have been treatment resistent. i am somewhat hopeful about amisulpride and mirapex, but, i have also been hopeful about a lot of things that didnt turn out...
>
> id love to here any info. please, ANYTHING.
>
> jon
You indicate that the medications poop out on you rapidly and if my memory serves me
correct in an ancient thread you indicated a significant family history
of bipolar disorder. Mood stabilizer meds (Depakote, Lamictal , Lithium, etc)
augmented to the base meds may help to prevent the poop out.John
Posted by Chris Doe on May 25, 2003, at 13:25:14
In reply to Re: any hope left for a dysthymic? » jonh kimble, posted by JohnX2 on May 25, 2002, at 1:27:08
I was just diagnosed with dysthymic disorder but have had the symptoms since 1992. I dont know if you've tried it yet but lexapro at 10mg a day has seemed to help me with at least a majority of my symptoms. I have also yet to experiance too many side effects at least none that compare to the depression itself. Hope this helps
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