Shown: posts 1 to 3 of 3. This is the beginning of the thread.
Posted by JohnX2 on April 1, 2002, at 7:45:17
Your comment"The second is a more global comment about psychopharm: regimens always are changing because people are always changing. It may be unrealistic to hope that there's some magic combination of meds that will work forever. We don't understand this entirely, but it's clear (particularly with SSRI's)that the body adapts to meds in ways that aren't always helpful."
My question:
Do you feel enough research is being spent trying to understand how the body adapts to our psychotropic medications after prolonged administration?
For drugs of abuse like cocaine and speed, I can dig up a zillion studies looking at every iota of detail of how these substances cause long term physiological adaptations. But for our psychiatric medicines: next to zilch.
John
Posted by Dr. Kramer on April 1, 2002, at 9:30:04
In reply to Kramer: medication regimens changing comment, posted by JohnX2 on April 1, 2002, at 7:45:17
>
> Your comment
>
> "The second is a more global comment about psychopharm: regimens always are changing because people are always changing. It may be unrealistic to hope that there's some magic combination of meds that will work forever. We don't understand this entirely, but it's clear (particularly with SSRI's)that the body adapts to meds in ways that aren't always helpful."
>
> My question:
>
> Do you feel enough research is being spent trying to understand how the body adapts to our psychotropic medications after prolonged administration?
>
> For drugs of abuse like cocaine and speed, I can dig up a zillion studies looking at every iota of detail of how these substances cause long term physiological adaptations. But for our psychiatric medicines: next to zilch.
>
> JohnAgreed! It's hardly the stuff Pharmaceutical Companies are going to sponsor, so it's got to come out of NIMH. Fact is, they don't get enough $ to do research, period.
Posted by JohnX2 on April 1, 2002, at 10:24:56
In reply to Re: Kramer: medication regimens changing comment, posted by Dr. Kramer on April 1, 2002, at 9:30:04
> >
> > Your comment
> >
> > "The second is a more global comment about psychopharm: regimens always are changing because people are always changing. It may be unrealistic to hope that there's some magic combination of meds that will work forever. We don't understand this entirely, but it's clear (particularly with SSRI's)that the body adapts to meds in ways that aren't always helpful."
> >
> > My question:
> >
> > Do you feel enough research is being spent trying to understand how the body adapts to our psychotropic medications after prolonged administration?
> >
> > For drugs of abuse like cocaine and speed, I can dig up a zillion studies looking at every iota of detail of how these substances cause long term physiological adaptations. But for our psychiatric medicines: next to zilch.
> >
> > John
>
> Agreed! It's hardly the stuff Pharmaceutical Companies are going to sponsor, so it's got to come out of NIMH. Fact is, they don't get enough $ to do research, period.This is a shame. Thanks for taking your valuable time to reply to my posts.
John
This is the end of the thread.
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