![[dr. bob]](/dr-bob-sm.gif)
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 10 of 10. This is the beginning of the thread.
Posted by paxvox on November 3, 2001, at 21:14:35
Hiyas. Anyone ever get abnormal blood test results on a CBC from AD meds? Specifically hemocrit (HCT), mean platelet volume (MPV), and hemoglobin (HBG). Any of the resident PBer (e.g. CAM) ever hear of such? Even though my blood chem was LOW in these areas, it was just a tad below the bottom of "normal".
PAX
Posted by paxvox on November 4, 2001, at 19:49:45
In reply to Blood Chemistry, posted by paxvox on November 3, 2001, at 21:14:35
I'll add to this list of symptoms: tachycardia. I have a consistant heart beat rate of 80-100 BPM. I think this is high, though 100 BPM is generally the accepted high-end limit. Does anyone taking Wellbutrin have this problem? Also, I have lost a whole lot more weight than I think is "normal" during WB therapy. Anyone else?
PAX
Posted by JGalt on November 4, 2001, at 21:45:17
In reply to Re: Blood Chemistry » paxvox, posted by paxvox on November 4, 2001, at 19:49:45
You *could be* mildly anemic. I had about half (some lower than 1/2, some higher) normal numbers on the tests you listed, as well as the increased pulse rate (at rest it was about 80-100, but if I stood up it went to around 140bpm). It turned out I had lost half my blood through a duodonal ulcer caused by NSAID's. Of course your symptoms could be a result of any of a number of other types of anemia (iron deficient, b-12 deficient, think there's 4 others). Hopefully others will post as to whether or not they've had this effect on Wellbutrin, but it doesn't sound typical, nor does it appear to me to be a cause of immediate concern. Provided your doctor knows about it, and you report it if symptoms get any worse (pulse gets higher, particularly upon standing, blood pressure starts getting consistantly lower, irritability, pale complexion, increased fatigue, increased exhaustion from less work).
Anyone else have any ideas that come to mind? This was just the first thing that I thought of, there could very well be many other causes that haven't occured to me yet.
Posted by Kaysey on November 5, 2001, at 3:33:41
In reply to Re: Blood Chemistry, posted by JGalt on November 4, 2001, at 21:45:17
According to the Physician's Desk Reference, use of Wellbutrin can be (with low probability) associated with anemia, leukocytosis, leukopenia, lymphadenopathy, pancytopenia and thrombocytopenia.
Kaysey
Posted by paxvox on November 5, 2001, at 13:18:16
In reply to Re: Blood Chemistry, posted by JGalt on November 4, 2001, at 21:45:17
Yes, I am at the low end of normal for RBC and hemocrit. My doc had tested me for having low red blood cell counts before a few years back. I don't think I have the more pronounced symptoms of any real anemia. I am cold, even during the summer, I have lost a lot of weight, but I attributed that to stopping alcohol, and the Wellbutrin. I would hate to have to try and find another AD, but if WB is the cause, I may have to, because the increased workload on my heart at 90+BPM will cause structuaral damage if it is unabated (so I have read). Hmmmm.....
Any others?PAX
Posted by Noa on November 5, 2001, at 15:06:51
In reply to Blood Chemistry, posted by paxvox on November 3, 2001, at 21:14:35
Recently, on a blood chem, I got a result of an elevated liver enzyme (sorry, I don't know which one it is). The doc had me consult a gastroenterologist who confirmed that my meds caused the elevation and it is such a non-specific indicator and not that elevated, that it isn't anything to worry about.
Posted by Kaysey on November 5, 2001, at 16:14:05
In reply to Re: Blood Chemistry, posted by Noa on November 5, 2001, at 15:06:51
> Recently, on a blood chem, I got a result of an elevated liver enzyme (sorry, I don't know which one it is). The doc had me consult a gastroenterologist who confirmed that my meds caused the elevation and it is such a non-specific indicator and not that elevated, that it isn't anything to worry about.
Periodically over the past 20 years I have had elevated liver enzymes (LDH and/or SGOT) reported on my chem-scans. At first, the physicians were extremely concerned, and I had to go through weeks of other tests (for Lupus, and other autoimmune disorders). Finally it was decided that certain meds and even my blood sugar level (after the required fast, my glucose often drops abnormally low and 'forces' the liver to work 'overtime' to ultimately get the sugar level back up) can impact the liver enzyme levels. Unfortunately (or fortunately), most physicians still at least require that I have repeat chem scans, and hepatitis panels, just to make sure that it isn't a false positive or actually hepatitis, etc.
I am not telling you to disregard your lab work, all I am saying is that I (and other people I have known) have had temporarily elevated liver enzymes, that are not indicative of major liver dysfunction.Kaysey
Posted by stjames on November 5, 2001, at 18:13:26
In reply to Blood Chemistry, posted by paxvox on November 3, 2001, at 21:14:35
It would be of great help to know "which" AD (s)
you are taking.james
Posted by Simcha on November 6, 2001, at 22:07:52
In reply to Re: Blood Chemistry » paxvox, posted by paxvox on November 4, 2001, at 19:49:45
Paxvox,
I've gained weight. I'm on 200mg WB SR/day with 40mg of Celexa... Maybe the Celexa cancels out the effect of the WB weightloss. ;-)
With a Larger Pants Size,
Simcha.
> I'll add to this list of symptoms: tachycardia. I have a consistant heart beat rate of 80-100 BPM. I think this is high, though 100 BPM is generally the accepted high-end limit. Does anyone taking Wellbutrin have this problem? Also, I have lost a whole lot more weight than I think is "normal" during WB therapy. Anyone else?
>
>
> PAX
Posted by paxvox on November 8, 2001, at 8:43:59
In reply to Re: Blood Chemistry, posted by stjames on November 5, 2001, at 18:13:26
I take Wellbutrin 150 SR x 2. And Tranzene 7.5 mg x 3.
PAX
This is the end of the thread.
Psycho-Babble Medication | Extras | FAQ
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.org
Script revised: February 4, 2008
URL: http://www.dr-bob.org/cgi-bin/pb/mget.pl
Copyright 2006-17 Robert Hsiung.
Owned and operated by Dr. Bob LLC and not the University of Chicago.