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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 4 of 4. This is the beginning of the thread.
Posted by kayjay on September 8, 2001, at 17:32:05
Can some body pleas tell me the difference between Adafinil and Provigil.
Thanks.
kayjay
Posted by JohnL on September 9, 2001, at 6:12:32
In reply to Adafrinil vs. Provigil, posted by kayjay on September 8, 2001, at 17:32:05
> Can some body pleas tell me the difference between Adafinil and Provigil.
>
> Thanks.
>
> kayjayHi Kayjay,
If you could look at a molecular diagram of Modafinil and Adrafinil, they look practically identical, with only the tiniest seemingly insignificant difference.I have tried both, and in reality they feel like two totally very different drugs. Modafinil for me was horrible. Yet Adrafinil for me is great. I find Adrafinil to be a much milder and yet much more effective medicine. And while Modafinil had a ton of side effects and nasty feelings, Adrafinil has none, for me.
Another big difference is the cost. Adrafinil is dirt cheap, Modafinil is very expensive. It's just my experience, but Adrafinil is by far my favorite. I hated Modafinil. There have been a couple people however who liked Modafinil a lot.
If you read about the mechanism of action of a commonly prescribed drug like Wellbutrin, they really don't know what it does or how it works. They offer some theories, but no one knows for sure. Well, it's the same with Adrafinil and Modafinil. I couldn't tell you exactly how they work. I do think however that Adrafinil is more specific in turbocharging norepinephrine chemistry by making alpha-1 receptors more responsive to noradrenaline, or making those receptors easier to bind to. Something like that. Modafinil on the other hand I believe has other mechanisms involving dopamine and who knows what else.
It's all just guesswork in reality. I can't tell you the exact differences between Modafinil and Adrafinil, only that one might work super while the other is horrible. They are supposedly similar on paper, but in reality not.
John
Posted by kayjay on September 9, 2001, at 14:46:35
In reply to Re: Adafrinil vs. Provigil, posted by JohnL on September 9, 2001, at 6:12:32
is because I tried Modafinl and hated it too. It caused my heart rate to be elevated, and actually made me feel more depressed. Sounds like the Adrafinl might be worth a try. Thanks again.
kayjay
Posted by djmmm on September 10, 2001, at 20:49:51
In reply to Thanks John, for your reply. The reason I asked , posted by kayjay on September 9, 2001, at 14:46:35
here is some info..
This is the end of the thread.
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