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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 4 of 4. This is the beginning of the thread.
Posted by 16# on August 12, 2001, at 1:10:10
I cannot get beyond a dosage of 25mg due to the cognitive dulling side effect of this drug. Has anyone experienced this and found a way around this problem?
Posted by JahL on August 12, 2001, at 12:22:07
In reply to Topamax Cognitive Dulling, posted by 16# on August 12, 2001, at 1:10:10
> I cannot get beyond a dosage of 25mg due to the cognitive dulling side effect of this drug. Has anyone experienced this
Seems to be a common side-effect. In a recent study Topomax was shown to have significant cognitive side-effects whereas Lamictal & Neurontin did not differ from placebo. I've heard it referred to 'Dumbomax" on this site. It's the main reason I haven't tried it.
> and found a way around this problem?
Dunno. Stop it?:-( [with pdoc consent etc etc]
J.
Posted by phillybob on August 12, 2001, at 21:34:50
In reply to Re: Topamax Cognitive Dulling » 16#, posted by JahL on August 12, 2001, at 12:22:07
> > I've heard it referred to 'Dumbomax" on this site. It's the main reason I haven't tried it.
Jah, while I had had some cognitive dulling in the beginning (very briefly), once I was above 125 mg/day +/-, I did not have such. In fact, when the topamax (stupamax is what I've heard) was workin' fine for me, I was definitely as sharp intellectually as I really should be. It was quite strange, but it worked as monotherapy for me quite amazingly (first time I felt good in years) until ... I experienced an intolerable and rare side effect (receding gums).
Anyway, everyone responds differently and has different needs. I would presume it's worth a shot for you.
[currently, 225 mg/day effexor and 150 mg/2X/day wellbutrin with pretty good response thus far!]
Posted by Kingfish on August 13, 2001, at 11:20:49
In reply to Topamax Cognitive Dulling, posted by 16# on August 12, 2001, at 1:10:10
The only way "around this problem", and it's not a complete fix, is to titrate up really slowly.
My experience with Topamax has been positive, for what it's worth. I had the cognitive problems for about a month or so even after I hit 250 mg, so it is a side effect, but it subsided then and it's been very helpful except for sedation with me. I haven't heard of anyone else having that problem though.
If you can handle feeling rather "drunk" for awhile (i.e. if it doesn't interfere with a job) it might still work for you).
- K.
This is the end of the thread.
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