Psycho-Babble Medication Thread 68646

Shown: posts 1 to 5 of 5. This is the beginning of the thread.

 

No response to Prozac after 5 wks, should I quit?

Posted by J on July 1, 2001, at 19:24:38

I've been taking 60mg Prozac for more than five weeks now. Sometimes I experience what I can only describe as a "quietning of my mind," which is the reason that I started Prozac - to get rid of constant obsessive thoughts. This response happens usually happens as soon as I wake up, but it doesn't last.

So should I stick it out for another few weeks? Waiting for an AD to kick in has to be one of the most frustrating ways a person can spend time.

Keep fighting,
J.

 

Re: No response to Prozac after 5 wks, should I quit?

Posted by SalArmy4me on July 1, 2001, at 19:45:13

In reply to No response to Prozac after 5 wks, should I quit?, posted by J on July 1, 2001, at 19:24:38

{Not from Medline}

Nierenberg, Andrew A. M.D et al. Timing of Onset of Antidepressant Response With Fluoxetine Treatment. American Journal of Psychiatry. 157(9):1423-1428, September 2000:

"The results of this study suggest that in a best-case scenario, more than half of the eventual responders to a fixed dose of fluoxetine will start to respond to treatment by week 2, with over 75% starting to respond by week 4. No predictors of time to response were found. These data show that if patients have not experienced an onset of response by weeks 4 or 6, they have about a 73%-88% chance of not exhibiting an onset of response by the end of the 8-week trial..."

 

Re: No response to Prozac after 5 wks, should I quit?

Posted by Bill L on July 2, 2001, at 7:55:11

In reply to No response to Prozac after 5 wks, should I quit?, posted by J on July 1, 2001, at 19:24:38

It sounds like you are getting a partial response. Just not a complete response. So that's a good sign. But 5 weeks is not enough time for a full response. I would give it another month. Why are you on such a high dose? Had you previously been on a lower dose?

> I've been taking 60mg Prozac for more than five weeks now. Sometimes I experience what I can only describe as a "quietning of my mind," which is the reason that I started Prozac - to get rid of constant obsessive thoughts. This response happens usually happens as soon as I wake up, but it doesn't last.
>
> So should I stick it out for another few weeks? Waiting for an AD to kick in has to be one of the most frustrating ways a person can spend time.
>
> Keep fighting,
> J.

 

Re: No response to Prozac after 5 wks, should I quit? » Bill L

Posted by J on July 2, 2001, at 20:40:34

In reply to Re: No response to Prozac after 5 wks, should I quit?, posted by Bill L on July 2, 2001, at 7:55:11

> It sounds like you are getting a partial response. Just not a complete response. So that's a good sign. But 5 weeks is not enough time for a full response. I would give it another month. Why are you on such a high dose? Had you previously been on a lower dose?

The Prozac dosage for OCD symptoms is usually higher than the normal dosage for depression. I started out at 60mg because I had previously taken 20mg without any effect at all - good or bad.

I suppose I should stick it out for another month. I read on PB that the time to response for OCDD symptoms can be as much as 8 weeks. It's just really hard to stick with something when you don't know whether it's going to work or not.

 

Re: No response to Prozac after 5 wks, should I quit?

Posted by Bill L on July 3, 2001, at 8:22:47

In reply to Re: No response to Prozac after 5 wks, should I quit? » Bill L, posted by J on July 2, 2001, at 20:40:34

I think that 8 weeks is a fair trial. If you feel better at 8 weeks, but not great, then give it longer. It can take a lot longer than 8 weeks to get a full effect. I also have OCD, along with anxiety and depression. I am doing good with Celexa.

> > It sounds like you are getting a partial response. Just not a complete response. So that's a good sign. But 5 weeks is not enough time for a full response. I would give it another month. Why are you on such a high dose? Had you previously been on a lower dose?
>
> The Prozac dosage for OCD symptoms is usually higher than the normal dosage for depression. I started out at 60mg because I had previously taken 20mg without any effect at all - good or bad.
>
> I suppose I should stick it out for another month. I read on PB that the time to response for OCDD symptoms can be as much as 8 weeks. It's just really hard to stick with something when you don't know whether it's going to work or not.


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