Psycho-Babble Medication Thread 67259

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Sal?-Tegretol: Anti-Dep. qualities??

Posted by katrina on June 20, 2001, at 15:14:29

My pdoc says that the tegretol can have AD qualities...any input?

 

Re: Sal?-Tegretol: Anti-Dep. qualities?? » katrina

Posted by SalArmy4me on June 20, 2001, at 18:43:51

In reply to Sal?-Tegretol: Anti-Dep. qualities??, posted by katrina on June 20, 2001, at 15:14:29

Schou, Mogens MD, DRMed, DrHCMult. Forty Years of Lithium Treatment. Archives of General Psychiatry. 54(1):9-13, January 1997:

"However, one may compare lithium with prophylactic alternatives. In a German multicenter study, unfortunately only partly published, which lasted 21/2 years, several hundred patients were randomly allocated to treatment with lithium or carbamazepine for bipolar illness and treatment with lithium or amitriptyline for unipolar illness. [41] Among the patients given the antidepressant drug, there were five suicides and no suicide attempts; among the carbamazepine-treated patients, there were four suicides and five suicide attempts; in the lithium-treated group, there were no suicides and no suicide attempts. The frequency of suicidal acts among the lithium-treated patients was significantly lower than the corresponding frequencies among those who were given antidepressants or carbamazepine (chi squared, P< .001 for both groups). These observations are consistent with the assumption that lithium treatment protects against suicidal behavior..."

> My pdoc says that the tegretol can have AD qualities...any input?

 

Better Answer » katrina

Posted by SalArmy4me on June 21, 2001, at 1:21:25

In reply to Sal?-Tegretol: Anti-Dep. qualities??, posted by katrina on June 20, 2001, at 15:14:29

http://www.vh.org/Providers/Conferences/CPS/10.html
Pharmacotherapy of Depression
Original Author: Paul Perry, Ph.D, BCPP
Latest Revisers: Paul Perry, Ph.D, BCPP, Dan Smith, Pharm.D., BCPP
Creation Date: 1996
Peer Review Status: Internally Peer Reviewed

"Post and Uhde (1985) reported a 54% (30/47) mild to moderate response rate to carbamazepine in a double-blind trial of acute depression. The responders to carbamazepine demonstrated statistically significant antidepressant response only after the first week of treatment. After the four week trial patients were placed on placebo with only mild and transient exacerbation of their illness. There was no relationship between carbamazepine blood levels and therapeutic response. More studies comparing carbamazepine to other antidepressants and placebo are needed to confirm these preliminary findings."

> My pdoc says that the tegretol can have AD qualities...any input?

 

Re: Tegretol Anti-Dep. qualities » katrina

Posted by Elizabeth on June 25, 2001, at 6:13:11

In reply to Sal?-Tegretol: Anti-Dep. qualities??, posted by katrina on June 20, 2001, at 15:14:29

> My pdoc says that the tegretol can have AD qualities...any input?

It's not as likely to work as the typical ADs, but it does work for some who do not respond well to ADs.

-elizabeth


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