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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 5 of 5. This is the beginning of the thread.
Posted by joe3749 on February 12, 2001, at 22:49:45
what are the possible dangers of overdosing on this medication. My wife is suffering from severe depression I would not want her to do something desperate with it.
Posted by Pandora on February 13, 2001, at 20:00:32
In reply to overdoseing, posted by joe3749 on February 12, 2001, at 22:49:45
Which medication is your wife taking? If you feel that she is in danger of harming herself, you need to act to protect her - speak with her doctor ASAP and/or consider inpatient treatment until she is no longer as distressed. Good luck.
Posted by joe3749 on February 13, 2001, at 22:55:15
In reply to overdoseing, posted by joe3749 on February 12, 2001, at 22:49:45
> what are the possible dangers of overdosing on this medication (remoron). My wife is suffering from severe depression and is taking this medication for it. I would not want her to do something desperate with it.
Posted by allisonm on February 14, 2001, at 2:46:03
In reply to Re: overdoseing, posted by joe3749 on February 13, 2001, at 22:55:15
Dear Joe,
From what I have read about Remeron, the chances of dying from an overdose are fairly remote unless paired with other drugs. I know when I was thinking about suicide often, my doctor only gave me short supplies of any drug. When I stabilized, he trusted me with a month's supply and then a month's supply with refills.
Here is a web site on Remeron:
http://www.rxlist.com/cgi/generic/mirtaz.htmHere is what that site says about Remeron overdose:
OVERDOSAGE
Human Experience
There is very limited experience with REMERON® (mirtazapine) Tablets overdose. In
premarketing clinical studies, there were eight reports of REMERON® overdose alone or in
combination with other pharmacological agents. The only drug overdose death reported
while taking REMERON® was in combination with amitriptyline and chlorprothixene in a non-
U.S. clinical study. Based on plasma levels, the REMERON® dose taken was 30-45 mg, while
plasma levels of amitriptyline and chlorprothixene were found to be at toxic levels. All other
premarketing overdose cases resulted in full recovery. Signs and symptoms reported in
association with overdose included disorientation, drowsiness, impaired memory, and
tachycardia. There were no reports of ECG abnormalities, coma or convulsions following
overdose with REMERON® alone.Overdose Management
Treatment should consist of those general measures employed in the management of
overdose with any antidepressant. There are no specific antidotes for REMERON®
(mirtazapine) Tablets. If the patient is unconscious, establish and maintain an airway to
ensure adequate oxygenation and ventilation. Gastric evacuation either by the induction of
emesis or lavage or both should be considered. Activated charcoal should also be considered
in treatment of overdose. Cardiac and vital signs monitoring is recommended along with
general symptomatic and supportive measures.In managing overdosage, consider the possibility of multiple-drug involvement. The physician
should consider contacting a poison control center for additional information on the
treatment of any overdose.CONTRAINDICATIONS
REMERON® (mirtazapine) Tablets are contraindicated in patients with a known
hypersensitivity to mirtazapine.
Posted by Noa on February 14, 2001, at 11:30:11
In reply to Re: overdosing » joe3749, posted by allisonm on February 14, 2001, at 2:46:03
If you are concerned about her overdosing, perhaps you should notify her doctor, and ask to go in to see him together to work out a plan for safety.
This is the end of the thread.
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