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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 3 of 3. This is the beginning of the thread.
Posted by Sigolene on September 11, 2000, at 6:29:26
I took only one paxil 10 mg and had first inflamation of urinary tract which stopped when i took benzodiazepine (because it's relaxing muscles i think). But during the night when benzo had finished it's effect, i had a real urinary infection that needed antibiotics. I would like to carry on Paxil but i'm really afraid of urinary infections horrible pain.
Has anyone already experienced urinary tract inflamation with Parxil, how long does it lasts ?
which solution is there for that ?
Thanks
Sigolene
Posted by Sunnely on September 12, 2000, at 0:46:52
In reply to Paxil and urinary infection. URGENT please., posted by Sigolene on September 11, 2000, at 6:29:26
> I took only one paxil 10 mg and had first inflamation of urinary tract which stopped when i took benzodiazepine (because it's relaxing muscles i think). But during the night when benzo had finished it's effect, i had a real urinary infection that needed antibiotics. I would like to carry on Paxil but i'm really afraid of urinary infections horrible pain.
>
> Has anyone already experienced urinary tract inflamation with Parxil, how long does it lasts ?
> which solution is there for that ?
> Thanks
> SigoleneHi Sigolene,
Paroxetine (Paxil), although an SSRI, still has anticholinergic effect. You seem to be very sensitive to this effect since it tends to become more evident in higher doses. One of the anticholinergic effects is urinary disturbance such as retention and/or inability to empty the bladder completely. This "residual" urine in the bladder serves as a "breeding ground" for infection.
Urinary tract infection (UTI) may become recurrent if "residual" urine continues to form due to the anticholinergic effect. Switching to an antidepressant with weak or no anticholinergic effect may be the best alternative.
Posted by dove on September 12, 2000, at 11:59:10
In reply to Re: Paxil and urinary infection. URGENT please., posted by Sunnely on September 12, 2000, at 0:46:52
I've had this same phenomenon with certain combinations of meds, with dose increases, and med initiation. Biggest culprits are the anticholinergic meds, even the mild ones that the doc's say don't cause these effects. I've had trouble with Amitripyline, Serzone, and the combo of Amitriptyline-Prozac-Wellbutrin.
I mostly ignored the first incident, lowering the dosage of all meds and it passed with 48 hours. Second time I tried to ignore the symptoms, but after 36 hours of truly despairing pain and no sleep I went in. I was told to never to wait that long again, and was prescribed antibiotics. With 24 hours there was a reality-defying improvement.
If the symptoms are mild, watch for any increase in pain, or a worsening of voiding. If you can hold out the effects should abate within a day or two. *Unless* you have the residual urine sitting immobile in your bladder, then you'll need to get the labs done and antibiotics initiated in a hurry. If you're feeling a little desperate and it's really bothering you, or keeps re-occurring, you may need to find a different med.
dove
p.s. Make sure and ask about pain-killers if you need them (i.e. which is better to use ibuprofen, aspirin, or acetaminophen).
This is the end of the thread.
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