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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 3 of 3. This is the beginning of the thread.
Posted by Ray on February 26, 2000, at 13:39:11
Hi everyone, I have 2 questions, the first is does anyone know if Effexor has a shelf life, and does it lose it's potency if not used by a certain date. My second question is I have been prescribed prilosec for acid reflux and wonder if that might reduce the effectiveness of effexor. By now I guess it's clear that I have been on Effexor for about 2 years and it worked great. Lately though it seems to be pooping out. In the beginning I took 75 mg. per day and it worked great. Now I take bt 300-400mg. per day. Some days are better than others. I also wonder if I should consider switching AD, or augmenting the Effexor. One last comment, I have been dieting and have restricted my carbohydrate intake greatly, could this be a factor.
Thanks for any feedback,Ray
Posted by Noa on February 26, 2000, at 19:57:22
In reply to effexor freshness prilosec, posted by Ray on February 26, 2000, at 13:39:11
One last comment, I have been dieting and have restricted my carbohydrate intake greatly, could this be a factor.
Could be. A lot of the popular diets these days severely restrict, in fact practically eliminate carbos. I think this is not healthy, and I do wonder if it has an effect on mood.
Posted by Cam W. on February 26, 2000, at 22:03:03
In reply to effexor freshness prilosec, posted by Ray on February 26, 2000, at 13:39:11
Ray - 1) Yes, Effexor has a shelf life. The expiry date would be on the bottle from the manufacturer. If the Effexor was from a pharmacy the shelf life would be hard to estimate (eg depends on how long the pharmacy had the bottle before using it to fill your prescription). A rule of thumb I use for precription bottles with no expiry dates is the meds are good for 1 & 1/2 years from the filling date. At the expiry date the drug is at least 95% of it's original potency. Most companies expire their drugs at 97-98%.2) The Effexor and Prilosec are metabolized by the same metabolic pathway in the liver; the cytochrome P-450-3A (CYP-3A3/4). While Effexor inhibits this pathway in very minor way, the increases in Prilosec plasma concentrations would be minimal and not clinically significant. Prilosec is neither a significant inhibitor or inducer of this metabolic pathway. In short, no, the Prilosec will not affect the Effexor and vice versa. - Hope this helps - Cam W.
This is the end of the thread.
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