![[dr. bob]](/dr-bob-sm.gif)
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 44 to 68 of 197. Go back in thread:
Posted by Mark on March 6, 2000, at 14:51:22
In reply to Re: Celexa-How can this be a good thing? MOM, posted by jamie on March 3, 2000, at 0:54:06
I have felt great since I started taking Celexa and dexadrine 5 weeks ago. I am take 20mg Celexa in morning, plus 20 mg dexadrine (for ADHD)in morning, and 10 mg. dexadrine at noon. I have also been exercising an average of 5 times per week, which seems to contribute to my feeling of well-being. My sex drive dropped almost immediately, but it has increased somewhat over the past two weeks. Even when the will is there, it takes much longer to achieve orgasm, but that is improving, too. I used to have a fairly high sex drive, averaging about 5-6 times per week, but now it is difficult to achieve orgasm more than 2-3 times per week. That ability is improving, but I still can't seem to maintain an erection while using a condom. I have not had any sleep problems. I don't really have dry mouth, but I do need to drink more water, although that is improving, too. I don't have any nausea, but my appetite has diminished (to a healthier level!) and have lost interest in junk food. So far the side effects of Celexa have been far fewer than with Prozac.
Posted by John Mazza on March 7, 2000, at 11:56:00
In reply to Celexa Side Effects Going Away, posted by Mark on March 6, 2000, at 14:51:22
Dear readers,
Please learn from my mistakes and stay away from drugs. If you're depressed e-mail me and I'll give you many recommendations. I am a reformed antidepressant user myself and I know the horrors of these drugs. Most importantly, everyone should be aware that the effects of serotonin elevating drugs (like Prozac) are long term and potentially irreversable. Don't Go There! If you do suffer from antidepressant drug brain damage, as I do, then e-mail me and I'll let you know what you should be doing to get better.
Best Wishes,
John
Posted by Veronica on March 7, 2000, at 12:05:01
In reply to Antidepressants Beware!, posted by John Mazza on March 7, 2000, at 11:56:00
> Dear readers,
>
> Please learn from my mistakes and stay away from drugs. If you're depressed e-mail me and I'll give you many recommendations. I am a reformed antidepressant user myself and I know the horrors of these drugs. Most importantly, everyone should be aware that the effects of serotonin elevating drugs (like Prozac) are long term and potentially irreversable. Don't Go There! If you do suffer from antidepressant drug brain damage, as I do, then e-mail me and I'll let you know what you should be doing to get better.
>
> Best Wishes,
>
> JohnI'm curious.
Posted by Fred on March 7, 2000, at 12:36:56
In reply to Re: Antidepressants Beware!, posted by Veronica on March 7, 2000, at 12:05:01
> I'm curious.
so am I. Why can't you post the information?
Posted by Scott L. Schofield on March 8, 2000, at 7:35:20
In reply to Antidepressants Beware!, posted by John Mazza on March 7, 2000, at 11:56:00
John
> > > John Mazza :
Dear readers,
Please learn from my mistakes and stay away from drugs. If you're depressed e-mail me and I'll give you many recommendations. I am a reformed antidepressant user myself and I know the horrors of these drugs. Most importantly, everyone should be aware that the effects of serotonin elevating drugs (like Prozac) are long term and potentially irreversible. Don't Go There! If you do suffer from antidepressant drug brain damage, as I do, then e-mail me and I'll let you know what you should be doing to get better.Best Wishes,
John
> > Veronica: I'm curious.> Fred: so am I. Why can't you post the information?
Hi John.Those are some pretty heavy-duty thoughts that you have shared with us here.
I'm sure that there are many people who will disagree with you with the same passion as you have demonstrated here. However, these people usually detail what experiences they have had, or sources of knowledge they have relied upon, to explain their passions.
So many of us here are stuck and gravely ill. None of our doctors' drugs seem to be helping much. If you are genuinely motivated by an altruistic desire to help change people's lives, you will, of course, share your thoughts and information with us now. I would be horrified to think that it is your intention to sell them.
I want to get better. I don't think you should be afraid of be making youself vulnerable to personal attacks. New and potentially effective alternatives are welcomed by most of us. In any event, I appreciate your providing our community here with your e-mail address.
I am eagerly awaiting your help.
Thanks.
Sincerely,
Scott
Posted by Matt B on March 8, 2000, at 10:47:55
In reply to Antidepressants Beware!, posted by John Mazza on March 7, 2000, at 11:56:00
I agree with John antidepressants that put their main focus on seretonin do pose some dangers. And that risk aint worth taking waiting months and feeling crappy until it decides to kick in. If the drug dont impact the neurotransmitter Dopamine then plan on searching and waiting and U might get lucky. Its too bad so many people abused amphetamine back in the day cause when taken properly more times than not itll get U through some of the difficult times. Ive been taking it for 2 years now at a normal dose taking a few days off here and there. Sure beats waiting months, some of us might not have made it that long.
We all have preferences and opinions
I wish everyone nuttin but the best
Matt B
Posted by Cindy W on March 8, 2000, at 21:16:47
In reply to Re: Antidepressants Beware!, posted by Matt B on March 8, 2000, at 10:47:55
> I agree with John antidepressants that put their main focus on seretonin do pose some dangers. And that risk aint worth taking waiting months and feeling crappy until it decides to kick in. If the drug dont impact the neurotransmitter Dopamine then plan on searching and waiting and U might get lucky. Its too bad so many people abused amphetamine back in the day cause when taken properly more times than not itll get U through some of the difficult times. Ive been taking it for 2 years now at a normal dose taking a few days off here and there. Sure beats waiting months, some of us might not have made it that long.
>
> We all have preferences and opinions
> I wish everyone nuttin but the best
> Matt BJohn and others, I respect your point of view, but have found that taking antidepressants is better than experiencing the profound pain due to OCD and depression. With the antidepressant (Effexor-XR), I feel I have closer to a "normal" life.--Cindy W
Posted by ruth on March 9, 2000, at 7:39:31
In reply to Re: Antidepressants Beware!, posted by Cindy W on March 8, 2000, at 21:16:47
> > Maybe I'm a skeptic, but I just can't help
but wonder why this Mazzo fellow isn't responding
to anyone asking him to please go into more depth
about his point of view...I'm not sure how fruitful
it is to just throw a big warning out without saying
why...
Posted by bob on March 9, 2000, at 19:03:43
In reply to Re: Antidepressants Beware!, posted by ruth on March 9, 2000, at 7:39:31
Well, I just don't know...I mean, HOW are we EVER going to get thru all this bad mojo and negativity if we keep taking ANTI-depressants?? I mean, shouldn't we be trying something POSITIVE or PRO or HAPPY instead? Sure, double negatives semantically may make a positive, but a psychological double negative is just two negatives too many. Maybe even three or four negatives too many.
Maybe there's just too much negativity bound up in what we're chattin' about here, doncha think??
[pardon me while I remove my tongue from my cheek]
bob
Posted by Carol on March 13, 2000, at 13:20:18
In reply to Re: Celexa and side effects -- do they end?, posted by Shelley in Seattle on February 2, 1999, at 16:04:38
> Hi, Tom:
>
> My experience with Celexa has been different, but it does seem that the side effects are getting milder. I didn't have the drowsiness problem (in fact, just the opposite!) I did have slight nausea but only for the first 3 days or so. I am just noticing that the constipation is clearing up, but the dry mouth is ever-present so I just drink a lot of water! The sexual delay is also still there -- but getting better.
> My doctor, and the MD I work for, both seem to think that these side effects will decrease. So far, they seem to be right.
>
> Good luck, Tom!
>
> Shelley
Hi,
I have been taking on Celexa few days ago. I noticed that it made me hungry and also I have been yawning all the time. Have you been before? I hope it will go away few weeks. Thanks, Carol
Posted by doug on March 13, 2000, at 18:02:44
In reply to Re: Celexa and side effects -- do they end?, posted by Carol on March 13, 2000, at 13:20:18
For daytime drowsiness, my doc suggested taking celexa in the p.m. instead of the a.m., which helped.However, the sexual side effects did not go away and the solution for me was to stop taking it. After stopping, I also noticed not having to go to the bathroom anywhere near as much. The lack of side effects has made me much happier. ;-)
Posted by Eliza on March 14, 2000, at 8:32:35
In reply to My experience with Celexa, posted by MA on February 29, 2000, at 9:46:05
I tried Prozac twice (4 months each time) and while the effects were immediate (the world going from black and white to color type thing) and I liked that kaleidoscopic shift, it made me feel better right away, over the long term, I found Prozac made me sleepy, I gained weight (and didn't care), and, most interestingly, since I know it supposedly kills libido, made me very promiscuous. I stopped taking it each time because it seemed to take the edge off of things after a while, and basically, I just didn't like myself on the drug. After a few years of sort of low-level depression (dysthymia?), I suffered another major depressive incident. I was feeling bleak, hopeless, etc. I started Celexa in October (I've been on it almost six months now). The effects were milder, more subtle than the effects with Prozac. I felt better gradually. Very minimal side effects at 20 mg. When I increased to 40 I got so drowsy (yawning constantly, going to bed at 8:30, not wanting to get out of bed in the morning) I cut myself back. I find my life is better all around, I'm happier, more hopeful, more confident, in a great relationship (since about Thanksgiving). At 20 mg. I don't have any noticable physical side effects. I don't have lowered libido or excessive drowsiness (although I probably sleep 7 to 9 hours on the drug, as opposed to 5 to 7 when I'm not taking anything). Unlike Prozac, I don't feel like a completely different person, and it isn't making me a fat zombie! I bought roller blades and I'm taking kickboxing and doing yoga and all in all just convinced that the pieces are all going to fall into place for me. I don't cry at all (not even watching a film like Life is Beautiful) and that's wierd for me since I've always been so hyper-sensitive (I mean, I'm the kind of person who cries during the Star Spangled Banner), but it's better than crying all the time. I was telling my therapist the other day that I do miss the depressed me at times, it's wierd to feel so good, to be so happy. At this point I know it's not all the Celexa, that it's my relationship, and the exercise, etc., but I do feel so noticably different and so much better than I've felt before, even at times in my life when things were "going well" so to speak, that I can't help thinking the Celexa isn't playing a major role. I'm thrilled with the drug; I'm sorry some of you are having problems with it. (Truth be told, I wanted Welbutrin, and begged my therapist to put me on it, but since I have a history of anorexia she negged that. I know other people who are taking it and they love it, especially as it makes them lose weight!). I do get concerned about long-term side effects (brain damage, etc.) and worry that I might pay a huge price down the road for the happiness I am presently enjoying. Maybe so. But I also know that the people who say it's a spiritual disease don't know what they are talking about. I have two degrees in religion, an MDiv, and I've been in therapy for years. I read and do yoga and listen to music and do all the right things, all well and good, but nothing has turned my life around in so real and visceral a way as this drug. Sorry to be so long, I've never posted anything before and wanted to share some of my thoughts, and some of my experiences with meds.
Posted by JH on March 15, 2000, at 10:07:31
In reply to Re: Antidepressants Beware!, posted by bob on March 9, 2000, at 19:03:43
> Well, I just don't know...I mean, HOW are we EVER going to get thru all this bad mojo and negativity if we keep taking ANTI-depressants?? I mean, shouldn't we be trying something POSITIVE or PRO or HAPPY instead? Sure, double negatives semantically may make a positive, but a psychological double negative is just two negatives too many. Maybe even three or four negatives too many.
>
> Maybe there's just too much negativity bound up in what we're chattin' about here, doncha think??
>
> [pardon me while I remove my tongue from my cheek]
> bobJohn, With comment like yours about antidepressants, and your lack of response, I really think you NEED to get back on the meds and face reality my friend.
Peace
Posted by LWS on March 16, 2000, at 7:40:10
In reply to Celexa Side Effects Going Away, posted by Mark on March 6, 2000, at 14:51:22
I started taking celexa 2 1/2 weeks ago to treat depression. This has been my first experience with any type of antidepressant. My problem has been the opposite of most people. Rather than being tired all the time, I seem to wake up frequently in the middle of the night. My doctor prescribed the drug, Sonata, which helps me fall back asleep, but I continued to wake up. He then suggested that I try over-the-counter Benedryl. That helps a bit, but I still wake up. Another side effect I've noticed is difficulty reaching orgasm. I'm feeling better menatally and want to continue with the celexa. Any suggestions or thoughts?
Posted by Alan on March 16, 2000, at 8:32:38
In reply to Waking up in the night, posted by LWS on March 16, 2000, at 7:40:10
> I started taking celexa 2 1/2 weeks ago to treat depression. This has been my first experience with any type of antidepressant. My problem has been the opposite of most people. Rather than being tired all the time, I seem to wake up frequently in the middle of the night. My doctor prescribed the drug, Sonata, which helps me fall back asleep, but I continued to wake up. He then suggested that I try over-the-counter Benedryl. That helps a bit, but I still wake up. Another side effect I've noticed is difficulty reaching orgasm. I'm feeling better menatally and want to continue with the celexa. Any suggestions or thoughts?
********************************************
Yes! I take Celexa and it is working well except for the same side effects for me.Trazadone for sleep at night - between 50 and 150mg is unbelieveably good for me. Hints: Take on an empty stomach and turn the lights out as soon as you start feeling sleepy...there is a window there after about 20min that lasts around 30min that is best to go to sleep. After that it becomes harder. I stay asleep all night. You can experiment with up to 250mg. Past a certain point though you won't feel like getting up in the morning so fast. The most important thing is that it helps normalise you brain waves for good sleep architecture. The others don't so you can sleep through the night and feel fatigued the next day because you haven't received the right type of sleep.
Try Wellbutrin starting with the 75mg tablet to augment the Celexa for anorgasmia. Works for alot of people. Go up on the dose until the symptoms subside or you start getting nervous from the drug.
Hope it helps!
Alan
****************************************
Posted by Barbara on March 16, 2000, at 19:45:25
In reply to Re: Waking up in the night -to LWS, posted by Alan on March 16, 2000, at 8:32:38
Yes! I take Celexa and it is working well except for the same side effects for me.
>
> Trazadone for sleep at night - between 50 and 150mg is unbelieveably good for me. Hints: Take on an empty stomach and turn the lights out as soon as you start feeling sleepy...there is a window there after about 20min that lasts around 30min that is best to go to sleep. After that it becomes harder. I stay asleep all night. You can experiment with up to 250mg. Past a certain point though you won't feel like getting up in the morning so fast. The most important thing is that it helps normalise you brain waves for good sleep architecture. The others don't so you can sleep through the night and feel fatigued the next day because you haven't received the right type of sleep.
>
> Try Wellbutrin starting with the 75mg tablet to augment the Celexa for anorgasmia. Works for alot of people. Go up on the dose until the symptoms subside or you start getting nervous from the drug.
>
> Hope it helps!
>
> Alan
> ****************************************
I absolutely agree with Alan about the Trazodone. It is like a miracle drug if you cannot sleep. But I also want to reiterate what Alan said about getting into bed and turning out the lights as soon as you take it - if you don't go to sleep right away, somehow you can't get to sleep once that first effect wears off. Its rather mysterious but once you are used to it, you just fall asleep and sleep like a baby. And not only are you sleeping well, which is always beneficial, you are getting the anti-depressant effect of Trazodone.As for the side effects of Celexa, right now I don't know if I am pitching or catching. I also take Wellbutrin, Dexedrine and Cytomel for ADD and a couple of weeks ago fell and broke some fingers in my right hand. Very painful. So into the chemical mix the doctor added Vicodin. Anyone here know of side effects such as depression with Vicodin. Or any others. I am just not myself. I take as little as possible and only at night. Just wondering if it was adding to depression. The injury itself could since it was my right hand. I cant do much for myself. Very frustrated.
Posted by Alan on March 16, 2000, at 23:35:37
In reply to Agree with Alan about Trazodone, posted by Barbara on March 16, 2000, at 19:45:25
> Yes! I take Celexa and it is working well except for the same side effects for me.
> >
> > Trazadone for sleep at night - between 50 and 150mg is unbelieveably good for me. Hints: Take on an empty stomach and turn the lights out as soon as you start feeling sleepy...there is a window there after about 20min that lasts around 30min that is best to go to sleep. After that it becomes harder. I stay asleep all night. You can experiment with up to 250mg. Past a certain point though you won't feel like getting up in the morning so fast. The most important thing is that it helps normalise you brain waves for good sleep architecture. The others don't so you can sleep through the night and feel fatigued the next day because you haven't received the right type of sleep.
> >
> > Try Wellbutrin starting with the 75mg tablet to augment the Celexa for anorgasmia. Works for alot of people. Go up on the dose until the symptoms subside or you start getting nervous from the drug.
> >
> > Hope it helps!
> >
> > Alan
> > ****************************************
> I absolutely agree with Alan about the Trazodone. It is like a miracle drug if you cannot sleep. But I also want to reiterate what Alan said about getting into bed and turning out the lights as soon as you take it - if you don't go to sleep right away, somehow you can't get to sleep once that first effect wears off. Its rather mysterious but once you are used to it, you just fall asleep and sleep like a baby. And not only are you sleeping well, which is always beneficial, you are getting the anti-depressant effect of Trazodone.
>
> As for the side effects of Celexa, right now I don't know if I am pitching or catching. I also take Wellbutrin, Dexedrine and Cytomel for ADD and a couple of weeks ago fell and broke some fingers in my right hand. Very painful. So into the chemical mix the doctor added Vicodin. Anyone here know of side effects such as depression with Vicodin. Or any others. I am just not myself. I take as little as possible and only at night. Just wondering if it was adding to depression. The injury itself could since it was my right hand. I cant do much for myself. Very frustrated.****************************************
Wow, what a cocktail you've got going there. Vicodin is definately a CNS depressant and who knows what's binding or working synergistically with what. This is always the problem being on so many meds at once - when an injury comes along it limits the course of treatment sometimes that will not upset the finely tuned balance you've acheived - at least temporarily.Any other options for pain? I took Tylenol #3's with alot of other stuff like you 'till the pain of a broken ankle went away. Sure I was sleepy but at least I could function. Seems there would be many other options for pain management for the time being. Did you talk over carefully with you pdoc the alternatives....seems as if they'd be most helpful in sorting things out like this. Be assertive always is my motto when it comes to meds....
All the best to you!
Alan
******************************************8
Posted by Barbara on March 17, 2000, at 14:53:13
In reply to Re: Agree with Alan about Trazodone, posted by Alan on March 16, 2000, at 23:35:37
> ****************************************
> Wow, what a cocktail you've got going there. Vicodin is definately a CNS depressant and who knows what's binding or working synergistically with what. This is always the problem being on so many meds at once - when an injury comes along it limits the course of treatment sometimes that will not upset the finely tuned balance you've acheived - at least temporarily.
>
> Any other options for pain? I took Tylenol #3's with alot of other stuff like you 'till the pain of a broken ankle went away. Sure I was sleepy but at least I could function. Seems there would be many other options for pain management for the time being. Did you talk over carefully with you pdoc the alternatives....seems as if they'd be most helpful in sorting things out like this. Be assertive always is my motto when it comes to meds....
>
> All the best to you!
>
> Alan
> ******************************************8
Its been an interesting time for me. Lost my job as result of injury. Stepped up plans to get married since not able to care for myself. This necessitated move away from my children and grandchildren. Wonderful man and no doubts about decision. But I started having nightmares and panic attacks after the accident (never a panic attack before!) So pdoc adds Neurontin to this mix (with the Vicodin). I was useless. In LALA land after one dose. Would have preferred small limited dose of Dalmane for sleep but he said no. But pain remains horrific since two fingers sheared off. So I am thinking maybe Darvon will help. Nope, they are like jelly beans. But voila, I remember being in Canada and getting (w/out an rx) Tylenol w/ codeine. So I have that also. It must be very mild because it does not make me sleepy. I think panic attacks (I feel like I am suffocating and going to die)are a result of (1) the sight of my injury was horrific - (2) so much drastic change in short time. Or could the Vicodin precipitate an attack? Very curious because of the mix.Thank you for your help!
Posted by Laura!!!! on March 30, 2000, at 18:22:55
In reply to Re: Sexual side effects?? Re: Celexa and side effects?, posted by Cindy W on December 29, 1999, at 10:46:24
Hello:
In my search for finding a solution for sexual disfunction due to anti-depressants, I came across a few articles and thought you might like to read them. I have also included a few website locations... I hope this helps!
Laura
__________________________________________________
In a somewhat novel application of ginkgo, researchers have studied its benefits in assisting patients suffering from anti-depression-induced sexual dysfunction, caused predominantly by selective serotonin reuptake inhibitors (SSRIs) (Cohen and Bartlik, 1998). The study was conducted in response to a case of a geriatric patient using Ginkgo biloba for memory enhancement who reported improved erections. The open study on 63 subjects found that women (33) were more responsive to the sexually enhancing effects than men (30), with relative success rates of 91% compared to 76% for the men. The ginkgo (product brand not noted) was given at a dosage range of 60 to 120 mg twice daily, within the normal range for the usual applications of ginkgo. The ginkgo reportedly had a positive effect on all four phases of the sexual response cycle: desire, excitement (erection and lubrication), orgasm, and resolution (afterglow). The authors note that the mechanism of action for this application is not yet clear. Postulated mechanisms include enhanced circulation to genitals by inhibition of PAF, direct effect on prostaglandins, known to enhance erectile function, and yet-to-be described norepinephrine receptor-induced effects on the brain.
HealthNews from the publishers of the New England Journal of Medicine
One of the most popular types of antidepressant—the class that includes Prozac—has a troubling downside: As many as 25 percent of people taking these drugs, called selective serotonin reuptake inhibitors, experience sexual problems, ranging from decreased sex drive to impotence and the inability to achieve orgasm. Some patients find the side-effects so distressing that they quit taking their medication.
A report in the October American Journal of Psychiatry shows that giving people a short break from treatment—known as a drug holiday—may improve their sex lives without sacrificing control of their depression.
Anthony Rothschild, MD, clinical director of the Mood and Anxiety Disorders Program at McLean Hospital near Boston, studied 30 people being treated for depression with Prozac, Zoloft, or Paxil. Each group of ten patients had taken one of the three drugs for an average of 15 months and had suffered sexual dysfunction for about a year. Over a four-week period, participants stopped their medication from Thursday morning until Sunday at noon. Half of those taking Zoloft or Paxil reported an improvement in sex drive, satisfaction, and ability to achieve orgasm during the weekend drug holiday without a significant increase in depression. The sexual problems returned shortly after patients restarted medication. The time-out wasn't as effective for the Prozac group, perhaps because this drug's effects take longer to wear off, Dr. Rothschild speculates.
While drug holidays show promise as a simple way to treat a notoriously difficult problem, Dr. Rothschild cautions that anyone having sexual difficulties while on these drugs should not interrupt treatment without a doctor's supervision. Further research with a larger group of patients will be needed to confirm that intermittent treatment keeps depression under control over the long term.http://panicdisorder.about.com/health/panicdisorder/msubmeds10.htm?iam=dp&terms=antidepressive+drugs
Posted by Cindy W on March 30, 2000, at 20:47:39
In reply to Reversing Sexual Side effects - POSSIBLE CURES...., posted by Laura!!!! on March 30, 2000, at 18:22:55
> Hello:
>
> In my search for finding a solution for sexual disfunction due to anti-depressants, I came across a few articles and thought you might like to read them. I have also included a few website locations... I hope this helps!
>
> Laura
> __________________________________________________
> In a somewhat novel application of ginkgo, researchers have studied its benefits in assisting patients suffering from anti-depression-induced sexual dysfunction, caused predominantly by selective serotonin reuptake inhibitors (SSRIs) (Cohen and Bartlik, 1998). The study was conducted in response to a case of a geriatric patient using Ginkgo biloba for memory enhancement who reported improved erections. The open study on 63 subjects found that women (33) were more responsive to the sexually enhancing effects than men (30), with relative success rates of 91% compared to 76% for the men. The ginkgo (product brand not noted) was given at a dosage range of 60 to 120 mg twice daily, within the normal range for the usual applications of ginkgo. The ginkgo reportedly had a positive effect on all four phases of the sexual response cycle: desire, excitement (erection and lubrication), orgasm, and resolution (afterglow). The authors note that the mechanism of action for this application is not yet clear. Postulated mechanisms include enhanced circulation to genitals by inhibition of PAF, direct effect on prostaglandins, known to enhance erectile function, and yet-to-be described norepinephrine receptor-induced effects on the brain.
>
>
> HealthNews from the publishers of the New England Journal of Medicine
> One of the most popular types of antidepressant—the class that includes Prozac—has a troubling downside: As many as 25 percent of people taking these drugs, called selective serotonin reuptake inhibitors, experience sexual problems, ranging from decreased sex drive to impotence and the inability to achieve orgasm. Some patients find the side-effects so distressing that they quit taking their medication.
> A report in the October American Journal of Psychiatry shows that giving people a short break from treatment—known as a drug holiday—may improve their sex lives without sacrificing control of their depression.
> Anthony Rothschild, MD, clinical director of the Mood and Anxiety Disorders Program at McLean Hospital near Boston, studied 30 people being treated for depression with Prozac, Zoloft, or Paxil. Each group of ten patients had taken one of the three drugs for an average of 15 months and had suffered sexual dysfunction for about a year. Over a four-week period, participants stopped their medication from Thursday morning until Sunday at noon. Half of those taking Zoloft or Paxil reported an improvement in sex drive, satisfaction, and ability to achieve orgasm during the weekend drug holiday without a significant increase in depression. The sexual problems returned shortly after patients restarted medication. The time-out wasn't as effective for the Prozac group, perhaps because this drug's effects take longer to wear off, Dr. Rothschild speculates.
> While drug holidays show promise as a simple way to treat a notoriously difficult problem, Dr. Rothschild cautions that anyone having sexual difficulties while on these drugs should not interrupt treatment without a doctor's supervision. Further research with a larger group of patients will be needed to confirm that intermittent treatment keeps depression under control over the long term.
>
> http://panicdisorder.about.com/health/panicdisorder/msubmeds10.htm?iam=dp&terms=antidepressive+drugs
Laura, thanks for sharing what you found! I'm glad people are finally being open about the sexual side effects of SSRI's, and hope that new antidepressants will be developed that don't take away what little pleasure there may be left in a depressed person's generally blah, bleak life!
Posted by Joe on March 30, 2000, at 23:17:59
In reply to Re: Celexa and side effects -- do they end?, posted by Carol on March 13, 2000, at 13:20:18
> I have been taking on Celexa few days ago. I
>noticed that it made me hungry and also I have
>been yawning all the time. Have you been before?
>I hope it will go away few weeks. Thanks, CarolI just started two days ago. I've found exactly
the opposite has happened...I seem to have lost
my appetite...(could be from the extreme nauseousness
it's given me though). I also seem to be getting
constant headaches from it. Hopefully this will
end soon.
Posted by bigbertha on March 31, 2000, at 2:39:55
In reply to Reversing Sexual Side effects - POSSIBLE CURES...., posted by Laura!!!! on March 30, 2000, at 18:22:55
> In a somewhat novel application of ginkgo, researchers have studied its benefits in assisting patients suffering from anti-depression-induced sexual dysfunction, caused predominantly by selective serotonin reuptake inhibitors (SSRIs) (Cohen and Bartlik, 1998). The study was conducted in response to a case of a geriatric patient using Ginkgo biloba for memory enhancement who reported improved erections. The open study on 63 subjects found that women (33) were more responsive to the sexually enhancing effects than men (30), with relative success rates of 91% compared to 76% for the men. The ginkgo (product brand not noted) was given at a dosage range of 60 to 120 mg twice daily, within the normal range for the usual applications of ginkgo. The ginkgo reportedly had a positive effect on all four phases of the sexual response cycle: desire, excitement (erection and lubrication), orgasm, and resolution (afterglow). The authors note that the mechanism of action for this application is not yet clear. Postulated mechanisms include enhanced circulation to genitals by inhibition of PAF, direct effect on prostaglandins, known to enhance erectile function, and yet-to-be described norepinephrine receptor-induced effects on the brain.
Hey Laura! Thanks for the info on gingko -no wonder
it's been around 400 million years. FYI - if site regulars
ever get to visit the city of Frederick, MD (not far from
Steven King's nightmare (FT Detrick AND Camp David!!).
Anyway, in the side yard of a fine period home that faces
the street, is a HUMUNGOUS gingko. The plaque on the fence
indicates that it was the LARGEST gingko in the US until the
mid-80's (I think). Apparently a larger tree was found in the
"wild" in north. BTW - and the ladies (ah heck, the guys are
running for the tape right now!) will love this - size
determination is based upon trunk circumference, but the one
in Frederick is still quite tall.Plus, one of the busiest shopping areas just outside the city
was landscaped with gingkos. Guess the shoppers will soon
bypass the grocery store and wait in line for their mouthful of
"love potion No.6,245,026.."
Posted by DC on April 1, 2000, at 2:34:39
In reply to Reversing Sexual Side effects - POSSIBLE CURES...., posted by Laura!!!! on March 30, 2000, at 18:22:55
In terms of sexual pleasure and potency Dexedrine seems to works wonders with me. I've tried ginko, it takes several months to start helping and it doesn't seem to work as well as dexedrine. I've also been on wellbutrin and noticed the enhancement from that, but again it was not as signicant as the Dexedrine. Have others had a similar experience with stimulants?
Posted by megan on April 2, 2000, at 0:05:45
In reply to Re: My experience with Celexa, posted by Eliza on March 14, 2000, at 8:32:35
> I tried Prozac twice (4 months each time) and while the effects were immediate (the world going from black and white to color type thing) and I liked that kaleidoscopic shift, it made me feel better right away, over the long term, I found Prozac made me sleepy, I gained weight (and didn't care), and, most interestingly, since I know it supposedly kills libido, made me very promiscuous. I stopped taking it each time because it seemed to take the edge off of things after a while, and basically, I just didn't like myself on the drug. After a few years of sort of low-level depression (dysthymia?), I suffered another major depressive incident. I was feeling bleak, hopeless, etc. I started Celexa in October (I've been on it almost six months now). The effects were milder, more subtle than the effects with Prozac. I felt better gradually. Very minimal side effects at 20 mg. When I increased to 40 I got so drowsy (yawning constantly, going to bed at 8:30, not wanting to get out of bed in the morning) I cut myself back. I find my life is better all around, I'm happier, more hopeful, more confident, in a great relationship (since about Thanksgiving). At 20 mg. I don't have any noticable physical side effects. I don't have lowered libido or excessive drowsiness (although I probably sleep 7 to 9 hours on the drug, as opposed to 5 to 7 when I'm not taking anything). Unlike Prozac, I don't feel like a completely different person, and it isn't making me a fat zombie! I bought roller blades and I'm taking kickboxing and doing yoga and all in all just convinced that the pieces are all going to fall into place for me. I don't cry at all (not even watching a film like Life is Beautiful) and that's wierd for me since I've always been so hyper-sensitive (I mean, I'm the kind of person who cries during the Star Spangled Banner), but it's better than crying all the time. I was telling my therapist the other day that I do miss the depressed me at times, it's wierd to feel so good, to be so happy. At this point I know it's not all the Celexa, that it's my relationship, and the exercise, etc., but I do feel so noticably different and so much better than I've felt before, even at times in my life when things were "going well" so to speak, that I can't help thinking the Celexa isn't playing a major role. I'm thrilled with the drug; I'm sorry some of you are having problems with it. (Truth be told, I wanted Welbutrin, and begged my therapist to put me on it, but since I have a history of anorexia she negged that. I know other people who are taking it and they love it, especially as it makes them lose weight!). I do get concerned about long-term side effects (brain damage, etc.) and worry that I might pay a huge price down the road for the happiness I am presently enjoying. Maybe so. But I also know that the people who say it's a spiritual disease don't know what they are talking about. I have two degrees in religion, an MDiv, and I've been in therapy for years. I read and do yoga and listen to music and do all the right things, all well and good, but nothing has turned my life around in so real and visceral a way as this drug. Sorry to be so long, I've never posted anything before and wanted to share some of my thoughts, and some of my experiences with meds.
Thank you, Eliza, I am about to start Celexa after years of trying Prozac, Wellbutrin, Zoloft, Paxil (what I am currently on and gaining immense weight). I hope my experience is similar to yours, I'm so tired of the side effects from drugs that are supposed to improve the quality of my life, and yet unable to do without meds because then the quality of life becomes so dreadful in my mind that I want to end it all. Wish me luck on Celexa, I hear mixed reviews. :)
Megan
Posted by gail on April 2, 2000, at 22:31:30
In reply to Re: My experience with Celexa, posted by megan on April 2, 2000, at 0:05:45
> Eliza,
what is your thought on staying on the celexa. I too have desthemia (sp?) and seem stable after 10 months on celexa and not sure if it is time to get off or if you ever get off.
gail
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