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Re: Mirtazapine worked really well for anxiety, but linkadge

Posted by TriedEveryMedication on March 24, 2021, at 19:04:13

In reply to Re: Mirtazapine worked really well for anxiety, but, posted by linkadge on March 24, 2021, at 15:42:54

> Mirtazapine does not have a significant affinity for 5-ht1a.
>
> See:
>
> https://en.wikipedia.org/wiki/Mirtazapine
>
> Keep in mind that larger numbers represent a LOWER affinity of the drug for that target. Mirtazapine exerts its strongest effect at the histamine 1 receptor. Hence you will notice that for the histamine receptor, the number is the smallest:
>
> H10.141.6 (highest affinity)
> 5-HT1A3,3305,010 (quite low affinity)
>
> Linkadge
>
>

Weird - on this page
https://en.wikipedia.org/wiki/Pharmacology_of_antidepressants

it shows mirtazapine's affinity to be 18 for HT-51A



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poster:TriedEveryMedication thread:1114223
URL: http://www.dr-bob.org/babble/20210120/msgs/1114254.html