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Re: 5HT2 antagonist without anticholinergic properties

Posted by Skeletor on November 17, 2020, at 15:11:08

In reply to Re: 5HT2 antagonist without anticholinergic properties jay2112, posted by Skeletor on November 17, 2020, at 15:07:41

This is kinda interesting: https://en.wikipedia.org/wiki/Deramciclane
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What is your take on Amoxapine?
https://en.wikipedia.org/wiki/Amoxapine
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For Pizotifen I get the following values from Ki Database https://en.wikipedia.org/wiki/Pizotifen

5HT1A... 200 - 1700 nM

5HT2A... 15.5 nM

5HT2C... 5 - 8 nM

I didn't find values for H1 and muscarinic receptors
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https://en.wikipedia.org/wiki/Ritanserin

Also quite strong at 5HT2
Then there is also stuff like Ketanserin, Pimavanserin etc.
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https://en.wikipedia.org/wiki/Nefazodone

Pretty perfect drug ^^

Never understood its ban.


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poster:Skeletor thread:1112581
URL: http://www.dr-bob.org/babble/20201025/msgs/1112597.html