Posted by undopaminergic on January 19, 2020, at 6:59:57
In reply to Re: selegine vs parnate, posted by rjlockhart37 on January 18, 2020, at 19:05:47
> i researched it, Parnate is for treatment resistant, is potent one. It effects MAO-B but also MAO-A partly,
>It has a slight preference for MAO-B, but it is usually regarded as non-selective. At moderate to high doses it potently inhibits both MAO-A and -B.
> i read reviews about depression, on websites, it has a high rating of depression treatment, but the only about Parnate is you have to take 3 times a day, or you'll have the fatigue,
>If you need the stimulant effect of it, yes, you have to take it more frequently, but for the MAO-inhibition, a single dose per day is enough.
I would say, it is better to take a stimulant additionally, rather than depend on the stimulant effect of tranylcypromine (Parnate).> Selegiline - its indicated for parkinson's disease,
And the EMSAM form is indicated for depression.
> which it is selective MAO-B, more selective than Tranylcypromine, that it increases dopamine levels, directly.
>They both do.
> That one of the reasons why its used in parkinson's. I read Tranylcypromine is not as effective as selegiline in parkinson's. ENSAM patch, many people ... here in the past had the patch, and i read good reviews of it. Seleigine yes, its metabolites are levoamphetamine, and amphetamine.
>Only the levo-isomers, of both amphetamine and methamphetamine.
> if there's any posters who know more info, that would be great, SLS, so many poster from the past that are gone now
>Yes.
-undopaminergic
poster:undopaminergic
thread:1108008
URL: http://www.dr-bob.org/babble/20200104/msgs/1108061.html