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Re: selegine vs parnate

Posted by undopaminergic on January 19, 2020, at 6:59:57

In reply to Re: selegine vs parnate, posted by rjlockhart37 on January 18, 2020, at 19:05:47

> i researched it, Parnate is for treatment resistant, is potent one. It effects MAO-B but also MAO-A partly,

It has a slight preference for MAO-B, but it is usually regarded as non-selective. At moderate to high doses it potently inhibits both MAO-A and -B.

> i read reviews about depression, on websites, it has a high rating of depression treatment, but the only about Parnate is you have to take 3 times a day, or you'll have the fatigue,

If you need the stimulant effect of it, yes, you have to take it more frequently, but for the MAO-inhibition, a single dose per day is enough.
I would say, it is better to take a stimulant additionally, rather than depend on the stimulant effect of tranylcypromine (Parnate).

> Selegiline - its indicated for parkinson's disease,

And the EMSAM form is indicated for depression.

> which it is selective MAO-B, more selective than Tranylcypromine, that it increases dopamine levels, directly.

They both do.

> That one of the reasons why its used in parkinson's. I read Tranylcypromine is not as effective as selegiline in parkinson's. ENSAM patch, many people ... here in the past had the patch, and i read good reviews of it. Seleigine yes, its metabolites are levoamphetamine, and amphetamine.

Only the levo-isomers, of both amphetamine and methamphetamine.

> if there's any posters who know more info, that would be great, SLS, so many poster from the past that are gone now






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