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Re: I knew spicy foods helped my depression

Posted by linkadge on January 17, 2020, at 9:11:55

In reply to Re: I knew spicy foods helped my depression phidippus, posted by linkadge on January 17, 2020, at 8:09:59

"For example, capsaicin, the active ingredient in hot peppers, is reputed to have euphoric properties. Capsaicin binds specifically to the vanilloid TRPV1 receptor and binds weakly to cannabinoid CB1 and CB2 receptors (7). In turn, activation of the TRPV1 receptor stimulates synthesis and release of the endogenous cannabinoid anandamide (8), which binds CB1 and CB2 receptors and is a weaker agonist at the TRPV1 receptor (9)."

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706955/


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