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Re: nicotine enhancment and dependence

Posted by undopaminergic on January 10, 2020, at 3:27:25

In reply to nicotine enhancment and dependence, posted by rjlockhart37 on January 9, 2020, at 23:15:11

> I've got to lower the levels, because truthfully, nicotine boosts my dopamine back to normal, and it releases another chemical called acetylcholine which helps thinking and process.

Nicotine is itself an agonist, at nicotinic acetylcholine receptors. Indeed, these receptors are named after it.

It also works on nicotinic receptors in the adrenal medulla to release adrenaline.

Are you saying it also causes the release of (endogenous) acetylcholine?

> I've got to lay down, taken nicotine lounges when i study,

What is a nicotine "lounge"? I've never heard that term before. Do you mean lozenges?

> and it does help but its not psychoative like real stimulants.

Yes it is. It is mainly centrally acting. It is also a "real" stimulant, but of course very different from cocaine- or amphetamine-like stimulants.

> Hopefully since i wrote this, ill go back and remind myself, vapes don't stink, they smell alot better, there less harsh on the lungs than tobacco, and people don't know you smoke.

I've used nicotine sublingual/bucchal tablets. Chewing gums did not work well for me. I am currently on a nicotine mouth spray, and it works very well, I haven't smoked in several months, and a bottle usually lasts more than a week. I get them for free from the hospital, and I've saved a lot of money from quitting smoking.

> The whole world from the 1940s-80s smelled like cigarette, classes, airplanes, restaurants, office meetings having cloud of cigarette smoke in the room. Nasty, that why people look down on smokers today.

Yes, I remember from the 80s many places, such as cafés used to smell of cigarette smoke, there were ashtrays in many places, and guests at our home used to smoke inside, and their own homes would smell tobacco all the time. My mother hates the smell, but I don't mind, I even kind of like it.

In one of my (hypo)manic episodes, I impulsively started smoking, and especially liked cigars. I chain-smoked them in my bedroom, and I closed the door to concentrate the smoke. I loved the haze of smoke, and the smell. I smoked in front of my computer and watched myself on the webcam, especially when my face disappeared behind a dense cloud of smoke as I exhaled. That is one of the happiest memories of my life.





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