Posted by SLS on December 1, 2017, at 21:13:36
In reply to Re: Everything is good, except for depression » SLS, posted by linkadge on December 1, 2017, at 15:18:24
Hi, Linkadge.
> As you mentioned, many people take desipramine without apparent significant cardiac effects.
I wish I knew how often CV side effects emerge with desipramine. I think your concern is well-founded. However, my impression remains that the absolute risk perceived by today's doctors is currently exaggerated.
> I suppose if there was a compelling reason that desipramine would provide a benefit that other medicaitons wouldn't then it would be worth a shot, with monitoring.My doctor was reluctant to add desipramine to Parnate, but had no problem with nortriptyline. Desipramine energized me in a way that nortriptyline did not.
> I do know that some health orginaziations discourage the use of desipramine for ADHD because of an apparent excess incidence of cardiac side effects.
>
> I would (personallay) look to explore other NRI's such as fetzima and/or nortriptyline.
>
> But hey, who knows.
>
> LinkadgeUnfortunately, some very important treatment insights and experience are disappearing as we lose older psychiatrists. These doctors found that some responders to desipramine did not respond to nortriptyline and vice-versa. Atomoxetine and reboxetine are extremely selective NE reuptake inhibitors. As antidepressants, they suck. I don't see that Fetzima is much better, despite its 5-HT reuptake inhibition. Of course, not being a doctor who has used it on multiple people, I don't know its true value. For me, milnacipran was inert.
All in all, I will keep my mind open about these things. You input is always appreciated by me.
- Scott
Some see things as they are and ask why.
I dream of things that never were and ask why not.- George Bernard Shaw
poster:SLS
thread:1096046
URL: http://www.dr-bob.org/babble/20161215/msgs/1096134.html