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Re: Studies to show doc for shorter MAOI)MAOI washout?

Posted by rjlockhart37 on September 7, 2017, at 21:04:51

In reply to Studies to show doc for shorter MAOI)MAOI washout?, posted by PeterMartin on September 7, 2017, at 16:36:38

"While it is generally safe to begin a different antidepressant after a 14-day washout, patients should be monitored closely after the washout period since there have been case reports of interactions, including serotonin syndrome, following 14-day washout periods.58 Similar caution should be exercised when switching from one MAOI to another, although more rapid switches (18 days) have been safely performed.57,59 A washout period of five half-lives for an antidepressant and its active metabolites should be provided before initiating an MAOI.57 This would require approximately a 45 week washout period for fluoxetine"

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2075358/


everything can change like that, and all these years go by so fast, but nothing lasts forever

 

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poster:rjlockhart37 thread:1094913
URL: http://www.dr-bob.org/babble/20161215/msgs/1094918.html