Posted by tony p on February 26, 2014, at 18:31:53
In reply to Re: cymbalta 30 /60, posted by Christ_empowered on February 24, 2014, at 6:39:17
> I think 60-120 is standard, but I'm clearly not an MD.
60 is the commonest, I believe. I'm fairly sensitive to most SSRIs & SNRIs (can't take Effexor *at all* because of S/E-mainly anxiety), but 30 is definitely not enough for me. I've most often taken 60, but had to raise my dose to 90 several times for a few months & it seems to have pooped out after several years. When I suggested 120 to my pdoc, his eyebrows shot up & he said "No." Well, that was the gist of what he said.
So I tried 120 on my own a while back, and got into a so-called "mixed" state -- agitated, irritable, some hypomania, certainly not depressed but not euphoric either. Altogether rather unpleasant. The impression I get from browsing & a couple of pdocs is that 120 is reserved for super-treatment-resistant depression and severe neurological pain.
I'm off the Cymbalta now, both because of poop-out & because my drug plan won't cover it -- most unfairly, I think. Cymbalta has received a "bad press" in the literature, which is all most plans go by -- in large samples it comes up less effective on average than Effexor, but that doesn't change the fact that FOR ME and thousands of others it's much the best SNRI. YMMV, as always.
Now on Cipralex going on a month, started at 10 mg/day, and now on 20 - that's always been the sweet spot for me for Cipralex. No S/E, which is great. However, without the NE component of the SNRI, I need a bit more Modafanil (& coffee!).
poster:tony p
thread:1061079
URL: http://www.dr-bob.org/babble/20140214/msgs/1061398.html