Posted by ed_uk2010 on June 1, 2013, at 8:49:09
In reply to Re: Amitriptyline, Perphenazine and Effexor XR » ed_uk2010, posted by F_minor on June 1, 2013, at 4:10:12
>I am on day 2 of effexor 75mg. I have tried escitalopram for some years and fluoxetine... i see on drug interactions that sertraline increases plasma concentrations of phenothiazines,like perphenazine... so i am not taking the risk.
Sertraline, citalopram/escitalopram and venlafaxine minimally effect the plasma levels of phenothiazines, there may be a slight change but nothing more. Fluoxetine and paroxetine may produce large increases in plasma levels and combinations with tricyclic antidepressants and phenothiazines are not a good idea. Since you have previously tried more than one SSRI, venlafaxine is probably slightly more likely to be effective than sertraline.
>Anyway, i cant up the dose of amitriptyline cause here in Greece it is sold as a combo with perphenazine
Really, how surprising! Amitriptyline is available on its own almost everywhere. Did you check with a pharmacist?
poster:ed_uk2010
thread:1044497
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