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Re: oleamide for anxious depression?

Posted by linkadge on July 13, 2011, at 14:17:01

In reply to Re: oleamide for anxious depression?, posted by BrainDamage on July 13, 2011, at 9:59:48

I think the effect of cannabis on anxiety is 'U' shaped. Lower activation increases hippocampal serotonin / norepinephrine release and decreases anxiety. Higher doses have a more anxiogenic effect also increasing locomotor hyperactivity.

The interesting thing about oleamide, is that it actually inhibits FAAH itself, meaning that it might inhibit its own metabolism and/or become more potent after chronic administration.

I am going to pick up some soy (which as I mentioned contains a few substances which inhibit FAAH). The combination of cocoa, soy and olive oil might be interesting.

Sleep is always a big issue for me. I'm hoping to find something as effective as amitriptyline for sleep with fewer side effects.

Linkadge


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