Posted by Roslynn on July 11, 2011, at 15:16:21
In reply to Re: Anyone had success with Savella for depression?, posted by bleauberry on July 10, 2011, at 19:35:39
Bleauberry,
Thank you so much for your helpful response. I'm sorry you were not able to take Savella long-term.
My pdoc has written the script for me to take 12.5 in the morning and 12.5 at night.I think he knows to start slowly w/me when dosing new meds.
My current meds are Prozac 40mg, clomipramine 50mg, lithobid 600mg, Seroquel 100mg and Ativan 1-2mg prn. The Prozac/clomipramine combo that had worked so well for me has pooped-out.
I've taken all the meds you mentioned below except I have not taken the Zoloft+Nortriptyline combo. But Zoloft alone makes me feel worse. I've taken Nortrip with Prozac but it didn't seem to do anything.Thanks again for your positive response concerning the Savella. I really appreciate it.
Best,
Roslynn> I like savella. After failing so many meds and then failing ECT, savella actually helped! It did what ECT couldn't.
>
> I had a side effect of urinary restriction which was quite troubling and potentially dangerous, so I had to stop. Other than that a decrease in appetite was about the only other major side effect. Stimulating the first few days and nights, but then really good sleep and more energy during the day.
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> A few other people here have tried it but didn't have the same effect as me.
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> It is my belief savella is dosed to high. I was only taking only 25mg....divided into 3 equal doses spread out. I just emptied the powder of capsules and divided it into 3 roughly equal piles and then reloaded each pile in an empty gel cap.
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> I think people can accidentally be pushed into not giving the drug a chance by having too high of a dose too fast, and then bailing out because of problems. Savella hits norepinephrine pretty hard, and I think the downstream circuits take more time to adapt than serotonin downstream circuits. Probably because they are intertwined with the endocrine system.
>
> Anyway, I am a fan of savella if managed properly. The only other things I might rule out before going to a maoi would be zoloft+nortriptyline; clomipramine; or some creative usage of prozac, zyprexa, ritalin.
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>
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> > Hi, my pdoc wants me to try Savella, I guess as a last-ditch effort before I would go to the MAOIs.
> >
> > Does anyone here still take Savella alone or in combo? What was your experience with it?
> >
> > Thank you!
> > Roslynn
>
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poster:Roslynn
thread:990636
URL: http://www.dr-bob.org/babble/20110630/msgs/990759.html