Posted by ed_uk2010 on August 14, 2010, at 16:15:53
In reply to Re: NARDIL / PARNATE Users Please Read » Willful, posted by angels78 on August 14, 2010, at 14:50:27
>"When you are switching from one MAOI to another, like with Nardil to Parnate, there is absolutely no need to taper, and there's especially no need for a wash-out period. You can safely switch INSTANTLY. That's what I did. If for some reason you DID need to stop taking Nardil for a wash-out period though, most sources say you can reasonably just STOP taking an MAOI. They don't have the same "discontinuation" issues that reuptake inhibitors have, and the whole idea of replacement occurring every day at a rate of 1/14th of the total inhibited enzymes (based on a 2-week "cycle") is pretty much a taper in its own right."
I don't know who this person is but they should not be telling people to do something which might be unsafe. The fact that one person was able to switch 'instantly' does not mean that it is safe for others to do so. The information about discontinuation symptoms is also inaccurate. Stopping MAOIs abruptly can cause discontinuation symptoms.
Also, enzymes are not replaced at the rate of 1/14th per day. This appears to be something which the writer has just invented.
The UK manufacturer of Nardil states: Phenelzine sulphate should not be administered at the same time as, or within 14 days of, treatment with other MAOIs.
poster:ed_uk2010
thread:958545
URL: http://www.dr-bob.org/babble/20100811/msgs/958593.html