Re: Treatment Resistant Depression.

Posted by linkadge on August 13, 2010, at 19:42:23

In reply to Treatment Resistant Depression., posted by bleauberry on August 13, 2010, at 19:33:52

I think its more complicated than that. I think that TRD is more hardwired.
"You can mess around all you want with serotonin, norepinephrine, dopamine etc. but if you don't have the right circutry in place, its not going to do anything" - a quote by Dr. Manjii.
I think TRD is probably related to mitochondrial decay, glial reductions, prefronal atrophy, decreased limbic interconnectivity, enlarged amygdala volume, decreased cortical grey matter, white matter hyperintensities, vascular insufficiancy etc. etc.
I personally think its a myth to believe that some magic chemical is going to come along and make it all better. It may take years of rehabilitative therapty for the brain to overcome such alterations.
Linakadge

Thread

Treatment Resistant Depression. bleauberry 8/13/10
Re: Treatment Resistant Depression. linkadge 8/13/10
Re: Treatment Resistant Depression. Phillipa 8/13/10
Re: Found it!!!!. Phillipa 8/13/10
Re: Treatment Resistant Depression. » bleauberry violette 8/13/10
Re: Treatment Resistant Depression. » violette Phillipa 8/13/10
Re: Treatment Resistant Depression. ed_uk2010 8/13/10
Re: Treatment Resistant Depression. » linkadge ed_uk2010 8/13/10
Re: Treatment Resistant Depression. sigismund 8/13/10
Re: Treatment Resistant Depression. » sigismund sigismund 8/13/10
Re: Treatment Resistant Depression. » bleauberry floatingbridge 8/14/10
Re: Treatment Resistant Depression. » linkadge SLS 8/14/10
Re: Treatment Resistant Depression. » linkadge bleauberry 8/14/10
Re: Treatment Resistant Depression. » ed_uk2010 bleauberry 8/14/10
...
Re: Treatment Resistant Depression. » weatherfreak Phillipa 8/25/10

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