Posted by g_g_g_unit on August 12, 2010, at 20:25:28
In reply to Re: effexor for ADD/anergic depression?or augment SRI?, posted by linkadge on August 12, 2010, at 12:30:16
> I would say that clomipramine would be more effective than effexor for atypical depression.
>
that's interesting. i thought TCA's were as a rule generally ineffective in atypical depression.why didn't you stay on clomipramine? how did it find its effects on cognition?
> Effexor only has weak effects on norepinephrine. It takes massive doses before noradrenergic effects are pronounced.
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> Although clomipramine is preferentially a SSRI, its metabolite, is essentially a selective norepinephrine reuptake inhibitor. I noticed that clomipramine dramatically improved my energy levels as compared to either an SSRI or effexor.
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> Clomipramine also improves sleep. The sleep disturbance from effexor or SSRI's can adversely effect daytime energy levels.
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> Linkadge
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poster:g_g_g_unit
thread:958238
URL: http://www.dr-bob.org/babble/20100811/msgs/958385.html