Posted by bleauberry on August 12, 2010, at 19:54:17
In reply to ultram + tramadol working, posted by floatingbridge on August 11, 2010, at 4:24:21
I think when I tried ultram I took too high of a dose (actually a low dose to most other people) and I felt really bad. Anything acting on serotonin does that to me. But just one pill every now and then shows hints of goodness...which tells me it is probably an endogenous endorphin deficiency involved with me, not serotonin or NE or DA. And maybe why a single vicadin tab is about a 90% cure of 15 year depression in about 3 hours.
Tramadol is combination NE reuptake, 5ht reuptake, and weak opioid. Unique. At boards where people rate their meds, tramadol happens to score better than all other antidepressants, even though the people who scored it that way initially started it for pain instead of depression. The antidepressant magic of it was discovered by accident.
Tolerance is an issue that affects many, but they usually find a maintenance dose that keeps working or take weekend drug holidays. Unlike antidepressants, it works when you come back to it after having paused.
If you ever need to stop it, withdrawal is universally a nightmare with just about everyone.
If it improves life quality a great deal for you, then the risks are well worth it, IMO. Better to be addicted and well than unaddicted and walking dead.
poster:bleauberry
thread:958228
URL: http://www.dr-bob.org/babble/20100811/msgs/958375.html