Posted by linkadge on August 12, 2010, at 12:30:16
In reply to Re: effexor for ADD/anergic depression?or augment SRI?, posted by ed_uk2010 on August 12, 2010, at 10:21:30
I would say that clomipramine would be more effective than effexor for atypical depression.
Effexor only has weak effects on norepinephrine. It takes massive doses before noradrenergic effects are pronounced.
Although clomipramine is preferentially a SSRI, its metabolite, is essentially a selective norepinephrine reuptake inhibitor. I noticed that clomipramine dramatically improved my energy levels as compared to either an SSRI or effexor.
Clomipramine also improves sleep. The sleep disturbance from effexor or SSRI's can adversely effect daytime energy levels.
Linkadge
poster:linkadge
thread:958238
URL: http://www.dr-bob.org/babble/20100811/msgs/958350.html