Posted by Vincent_QC on January 12, 2010, at 8:46:12
In reply to Re: SSRI with the less initial increase anxiety..., posted by Meltingpot on January 11, 2010, at 14:08:53
> Vincent,
>
> Believe me I too know what real side effects are from SSRIs, I experienced terrible anxiety on Remeron, Seroxat, prozac and Sertraline when I started on the drug merry go round in 2001, the anxiety would last all day and I would feel weak from it in the evening. Fortunately the Zyprexa was a God send for me which is why it is such a shame it hasn't helped you.
>The main problem with the antidepressant avaible in the Canada or the USA is that they block the reputake of a lot of receptors, who lead to an increase level of those neuroceptors and a terrible increase of the anxiety at first...
In the Europe, they have some antidepressants meds who seem to be a lot smarter than the ones in the USA or Canada like the Stablon (Coaxil) or the newer Valdoxan... 2 meds that I will not be able to try, unless I order them from the web... and even, I don't trust online order and don't know if it can be possible to do it...
Also, like I wrote before, the Zyprexa will decrease your anxiety because it's hit really hard the H1 receptor, who mean that you will feel sedated... so more relaxed (in theory)... but will also make you gain weight very fast and affect your cognitive abilities as well...
In my case, I don't find those kind of meds helping at all... they just mask the anxiety and make me a lot more tired, mean more irritable and anxiety always return in a higher state after they stop working...
Also, I already take the Klonopin (Rivotril - Clonazepam) to a high dose everyday. 8 mg a day is a really strong dose... so every meds who works on the Gaba receptors will not be very usefull also since it's seem that my gaba system is already saturated of more gaba_a neurons and even if I take more if Klonopin, I will not feel less anxious...
> I know you had a problem with the clomipramine but I'm sure if you had got up to five weeks on it you would have been ok. But then you don't seem to have the reassurance of having something to help with the anxiety.
The TCA'S are dirty meds... they hit too many receptors for nothing... and they are toxic for the heart. Most of the peoples on those meds will not notice the high blood pressure and the higher pulse rate while they will be on those meds... but in a long term view, they are the worse meds for the heart.
Also, I don't think adding a beta-blocker will help... since all the TCA's increase the blood concentration of the beta-blocker, making them very dangerous to use at the same time...
Just one more thing on the Beta-blocker... I try a lot of them... they never help as well... it's adding fatigue for nothing, and don't prevent the rapid heart beat, who is responsible of the panic attacks most of the time for me!!!
I try also an older anti-hypertensive drug call "Clonidine"...because I had read some studies about it and the panic disorder and it didn't help at all, I had more panic attacks while I was taking it...
And no, I don't have a good support from my PDoc or anyone else. I don't work so I don't have the money to pay for a private Therapist for a CBT, I Can't have a free therapy because the wating list in here is very long...and most of the time, all the PDoc didn'T seem to care about their patients at all... they just RX meds and return you to home and forget about you...
>
> When you are not on SSRIs and are not experiencing side effects but still experiencing anxiety, do the physical symptoms come first before the anxious thoughts or is it the other way around?
>My anxiety is always there... From the moment I open my eyes in the middle of the night , until I close them when I go to the bed... It's not a matter of thoughts now, it's always there. Before, I had mostly panic attacks trigger by some physical symptoms like the rapide heart beat... or the dizness... but now it's 24h on 24 h...
But, the anxiety is there before the physical symptoms for sure... the symptoms just amplify the anxiety...
> I used to be very scared of dying before my depression and anxiety resurfaced but I no longer am so much as I can't think of a worse state to be in than the way I feel off all medication. I'd rather be dead than have to live like that for the rest of my life. I'm older than you so maybe that also has something to do with it. However, we all have to die sometime and we were all dead for millions of years before we were born, at least I think we were, so we are just going back to the same state as before. Then again if I was close to death then I'm not sure I would feel the same way ;-) I'm wondering if you are a Catholic though, I am.
>No, i'm not Catholic... my family are but not me.... I don't believe in God or anything else and I don'T think believing in something like GOD will help me to have less anxiety from the death and the unknow... I see my grand-mother pray all her life and she die from the cancer in a very painfull situation and distress!!! You know what I mean?... Religion will certainly not help me... and I will stop talking about religion because I feel that I will be ban from here if I don't stop !!! lol
> What about beta-blockers have you tried them along with tricyclics, they are supposed to help with heart rate and blood pressure. Maybe you could ask your doctor if it would be safe to try them along with an antidepressant.
>Like I write before, they don't help... Propanol, Bisoprolol, Metoprolol, name them... I try all of them without any success in reducing my panic disorder... Also, being on a beta-blocker just worse everything because you canno't exercise because of the terrible fatigue and muscles pain they produce. Most of the time, when you are on a beta-blocker, you feel just like you will die because you feel weak and you have a lot of dizness and no physical strenght...
Beta-blocker are only good for peoples with real heart disease... they don't even help for the situational exposure anxiety like when it's time do to a public speech...
> Hope you feel better soon.
>
>
> Denise
>
>I hope also....
>
>
poster:Vincent_QC
thread:933130
URL: http://www.dr-bob.org/babble/20100103/msgs/933347.html