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Re: Hope this helps

Posted by willey on January 5, 2010, at 12:58:06

In reply to Highest dose of Nardil users have taken?, posted by julie1977 on January 5, 2010, at 10:41:42

This is in no way,no how,me advocating any dose average of this drug.In fact having never been on it but for a week i dont even know what is standered dose,however this article sounded like it might come of some use,

http://archpsyc.ama-assn.org/cgi/content/abstract/35/5/629

*******Our data show that a safe, effective phenelzine dose is 1 mg/kg body weight per day.*****


"Abstract

There is renewed interest in the clinical pharmacology of phenelzine sulfate and other monoamine oxidase (MAO) inhibitors. Newer clinical and analytic techniques recently have been applied to investigations of this class of drugs in man. The results show that drugs such as phenelzine are effective in nonendogenous depression and phobic disorders. Clinical response to phenelzine is related to platelet MAO inhibition and dosage per unit body weight. High percent MAO inhibition in platelets at two weeks is associated with greater improvement after a six-week course of treatment. Our data show that a safe, effective phenelzine dose is 1 mg/kg body weight per day. These results have delineated the pharmacologic and therapeutic effects of phenelzine and support a continuing role for MAO inhibitors in psychopharmacology."


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poster:willey thread:932558
URL: http://www.dr-bob.org/babble/20100103/msgs/932575.html