Posted by linkadge on September 27, 2009, at 16:05:57
In reply to Re: Agomelatine superior to Fluoxetine, posted by bleauberry on September 26, 2009, at 18:02:03
I don't know how well it will work in those who have been previosly exposed to reuptake inhibitors.
I personally think reuptake inhibitors induce adaptive responses that can last much longer than the period of drug administration. So, if you come off something like parante and go onto something with a seemingly much gentler clinical action, it may take a while to respond.
I think agomelatine is probably going to be more effective in AD naive patients. But I do think, if it is effective, that it could produce a higher rate of remission, in the sense that there will likely be a relative absense of side effects.
Linkadge
poster:linkadge
thread:918415
URL: http://www.dr-bob.org/babble/20090921/msgs/918736.html