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Re: Need for Serotonergic component in treatment? » linkadge

Posted by Bob on September 21, 2009, at 21:37:03

In reply to Re: Need for Serotonergic component in treatment?, posted by linkadge on September 21, 2009, at 19:45:01

> I certainly wouldn't say there is a need - but I don't know. Agents like seroquel have some marked antidepresant properties but no marked serotonin enhancing effect. There is wellbutrin too. Depends on the depression I guess.
>
> Nortriptyline had *some* ad effect for me, but amitriptyline has been better.
>
> Linkadge
>
>

You're on amitriptyline now? Do you have any theories as to why it might be better than Nortriptyline for you?

Isn't amitriptyline a 'dirtier' med? I thought it had heavy anticholinergic effects including weight gain and sedation.

 

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