Posted by bulldog2 on August 15, 2009, at 13:04:56
In reply to hydromorphone in combination with six other meds, posted by doxogenic boy on August 15, 2009, at 9:08:10
> Hello to all of you.
>
> I have treatment-resistant depression, obsessive-compulsive disorder, generalized anxiety disorder and social phobia, which I have had most of my life. A problem that is part of this, did I mention in the newbie group (things take long time for me to do because it has to be so circumstantial).
>
> My current combination is:
>
> quetiapine 600 mg (200 + 100 + 100 + 200 mg)
> liothyronine sodium 20 mcg (20 mcg in the morning)
> escitalopram 40 mg (40 mg in the morning)
> tianeptine 150 mg (4 tablets 12,5 mg three times a day)
> clonazepam 1 mg (1 mg at bedtime)
> trimipramine 100 mg (100 mg in the evening)
>
> Friday 8/7/09 hydromorphone immediate release 3,9 mg (1,3 mg three times a day) was added and Thursday 08/13/09 I started with 4 mg sustained release capsules, Friday 08/14/09 4 mg twice a day.
>
> I think all of the medicines contribute to the antidepressant effect, and most of them also to the anxiolytic effect, because I experienced an improvement when each of them was added, but it was the hydromorphone that gave it the finishing touch.
>
> This is the 9th day with the hydromorphone combination. I have not felt any euphoria, but I feel calm and a little more confident. My worries are there, but they just pass away without scaring me. Usually, I am insecure and anxious.
>
> What I would like to get advice about, is what I can do if I experience tolerance for, or loss of effect of the hydromorphone. It has been nasty when I have had a hope to a medication to get me into remission, when it stops working.
>
> And I wonder how the SSRI/SSRE combination works, as they theoretically should cancel each other out? What about hydromorphone/tianeptine, could there be a synergetic anxiolytic effect?
>
> (I get all of the medication on prescription, and I ask my psychiatrist if I will change anything).
>
> I want to write much more about this, but I think it is time to post, to get started. :)
>
> doxogenicI take neurontin 1200 mg twice a day and percocet 10 mg 4-6 times a day. This is for hip pain that has to be replaced.
Very good combo for anxiety and is a potent antidepressant.
Try a drug holiday now and than to maintain med potency.
Afer surgery will be transferred to self administered pump morphine and than put back on percocet.Eventually have to wean off.
They will let me stay on neurontin. I was thinking of going to parnate and nortriptyline.
So again to you, drug holidays now and than.or use other drugs in place of yours now and than.
I find shifting meds around maintain potency.
poster:bulldog2
thread:912227
URL: http://www.dr-bob.org/babble/20090810/msgs/912252.html