Posted by desolationrower on January 25, 2009, at 11:18:45
In reply to Let's make a list of hypnotics - sleep medications, posted by SLS on January 24, 2009, at 9:28:53
well i think melatonin should be on the list, i find it helpful for sleep cycle to be kept regular and not getting into pattern of staying up late, sleeping in late, etc. also can be combined with others no problem; it is kind of a building block in getting things right, since just about everyone has unnatural levels of light after dusk. and agomeltaine would likely be useful too i think it will be seen this way after a while.
And i've mentioned cyproheptadine being the antihistamine that is sort of ideally designed for sleep.
Also, i've found clonidine to be VERY sedating.
also, as someonementioned GHB, phenibut can be helpful, although tolerance and addiction risks would keep me from using it regularly. but if you started an MAOi and need some sleep occasionally, it could be usable. I'd be doubleplus carful if you also have other hypnotics.
a basic d2 might be relevant here, as well. excess dopaminergic signalling might be involved, although i'm not sure. Certainly, DA agonists can make some people have symptoms like narcolepsy. but low dose DA agonists are likely reducing DA signalling, so an AP might work as well, and would probably be easier to explain to a pdoc. I think both d1 a d2 blockade would be good, and 5th2a would be good as well. I'm not sure which AP would be ideal.
-d/r
poster:desolationrower
thread:875767
URL: http://www.dr-bob.org/babble/20090104/msgs/876055.html