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Re: The odds ... are there » fca

Posted by yxibow on January 6, 2007, at 13:56:04

In reply to The odds in perspective--it is, posted by fca on January 6, 2007, at 11:41:32

> not 1/3 of persons it is "from Medscape:
>
> Priapism associated with trazodone usage has been reported with a frequency ranging between 1 in 1000 and 1 in 10 000 and does not appear to be dose related.[3] In both the urological and psychiatric literature, trazodone-induced priapism is more frequently reported than that with any other psychotropic medication. However, this may be related to the widespread prescription of this antidepressant, particularly in the US.[1]
>
> There are wide variations in the interval between initiation of drug therapy and the onset of priapism. However, the data reported to the US Food and Drug Administration suggest that this complication is most likely to occur within the first 28 days of treatment.[4]

Oh goodness no, its MUCH more common than the monograph. Its an awful way to go to sleep too in my opinion, staggering, low blood pressure on the way to bed, passing out if you've had ANY alcohol before, and oh, the lovely priapisms. I had them several times. No joke, I got rid of it by standing on my head in bed and my feet on the walls so the blood went the other way... But for older patients especially, this can be, as noted, damaging or dangerous for the penis.

I'm a strong believer in sleep medicines for sleep, e.g. Rozerem, Ambien/CR/regular, etc... and not side effect meds, especially Trazodone. Remeron may be a different story other than its weight gain. Trazodone also has the metabolite mCPP, which can cause psychosis in patients susceptible to psychosis (not saying you are.)

Do mention this to your doctor and find another medication I would think, if not willing to prescribe the pseudobenzodiazepines that I mentioned (Rozerem isnt, its a melatonin receptor agonist), than at least Remeron or doxepin.

-- Jay

 

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URL: http://www.dr-bob.org/babble/20070101/msgs/719867.html